UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	B0393.3	B0393.3	0	chrIII 4,758,450	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR006553 (Leucine-rich repeat, cysteine-containing subtype)
2	R53.6	R53.6	n/a	chrII 9,969,060	contains similarity to Pfam domain PF03651 Partner of SLD five, PSF1 contains similarity to Interpro domain IPR005339 (GINS complex, Psf1 component)
3	fem-3	C01F6.4	n/a	chrIV 9,106,267	fem-3 encodes a novel protein that promotes male development in all tissues.
4	F40F11.3	F40F11.3	n/a	chrIV 11,592,569	contains similarity to Saccharomyces cerevisiae involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; SGD:YDL058W
5	meg-2	K02B9.2	n/a	chrX 13,924,518	meg-2 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-2 activity by itself results in no obvious abnormalities, but loss of meg-2 activity in meg-1 mutant animals indicates that meg-1 and meg-2 likely have redundant functions in germline development; meg-2 may also function redundantly with mes-1; meg-2 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; a GFP::MEG-2 fusion protein localizes exclusively to P granules in the embryonic germ cell lineage.
6	F54D10.5	F54D10.5	n/a	chrII 3,807,652
7	C02B10.2	C02B10.2	n/a	chrIV 5,090,651	contains similarity to Homo sapiens SNARE-associated protein Snapin; ENSEMBL:ENSP00000357674
8	meg-1	K02B9.1	n/a	chrX 13,928,257	meg-1 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-1 activity via mutation and RNAi indicates that MEG-1 is required for germline development and normal levels of fertility; specifically, MEG-1 is required maternally for normal germ cell proliferation and/or survival and for fully normal P granule segregation to the germ cell lineage; in regulating germline development, meg-1 likely functions redundantly with meg-2 and mes-1; meg-1 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; meg-1 mRNA is expressed in the proximal germline; MEG-1 localizes to P granules from the 4-to-8-cell through 100-cell stage of embryogenesis; MEG-1 localization to P granules partially requires MES-1 and, in turn, MES-1 localization to P granules is partly dependent on MEG-1.
9	C17E7.4	C17E7.4	n/a	chrV 3,893,699
10	rgs-10	F45B8.2	n/a	chrX 14,963,378	C. elegans RGS-10 protein; contains similarity to Pfam domain PF00615 Regulator of G protein signaling domain contains similarity to Interpro domains IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
11	taf-11.2	K10D3.3	n/a	chrI 7,133,402	C. elegans TAF-11.2 protein; contains similarity to Pfam domain PF04719 hTAFII28-like protein conserved region contains similarity to Interpro domains IPR006809 (TAFII28-like protein), IPR009072 (Histone-fold)
12	C50E3.13	C50E3.13	n/a	chrV 7,623,254
13	nhr-263	F10G2.9	n/a	chrV 7,341,043	C. elegans NHR-263 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	mel-47	EEED8.1	n/a	chrII 5,421,944	C. elegans MEL-47 protein; contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
15	C27C12.3	C27C12.3	n/a	chrX 14,864,682	C27C12.3 encodes a novel protein that is conserved in C. elegans; three other genes related to C27C12.3 are present in tandem on the X chromosome; in situ hybridization studies indicate that C27C12.3 mRNA is expressed in the proximal germline.
16	C16A3.2	C16A3.2	n/a	chrIII 6,390,183	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
17	F01F1.11	F01F1.11	n/a	chrIII 5,870,989
18	F48C1.5	F48C1.5	n/a	chrI 5,317,876
19	K03H1.7	K03H1.7	n/a	chrIII 9,947,654	contains similarity to Saccharomyces cerevisiae major low affinity 55 kDa Centromere/microtubule binding protein; SGD:YLR175W
20	F32D1.6	F32D1.6	n/a	chrV 4,374,245
21	ZC477.5	ZC477.5	n/a	chrIV 7,102,332
22	bath-41	F37A4.9	n/a	chrIII 6,721,274	The F37A4.9 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
23	nos-1	R03D7.7	n/a	chrII 10,952,444	nos-1 encodes an putative RNA-binding protein that contains a zinc-binding motif homologous to that of Drosophila Nanos, a posterior-group protein required for embryonic patterning and primordial germ cell development; in C. elegans, NOS-1 is required redundantly with NOS-2, a second Nanos homolog, for maintenance of germ cell viability during postembryonic development and for preventing primordial germ cells from dividing in the absence of food; nos-1 mRNA is expressed dynamically in the embryo, with early expression seen throughout the embryo and later expression restricted solely to germline blastomeres; nos-1 mRNA becomes undetectable after the 200-cell stage, but reappears later at the 550-cell stage; NOS-1 protein is not detectable in germline blastomeres until the 550-cell stage, suggesting that NOS-1 might actually function zygotically in germline specification.
24	try-1	ZK546.15	n/a	chrII 4,948,807	C. elegans TRY-1 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine), IPR008256 (Peptidase S1B, glutamyl endopeptidase I)
25	T01G5.7	T01G5.7	n/a	chrV 15,112,773	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
26	F52B5.2	F52B5.2	n/a	chrI 8,317,068	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
27	C17H11.4	C17H11.4	n/a	chrX 8,181,277	contains similarity to Drosophila melanogaster Flybase gene name is ari-1-PC;; FLYBASE:CG5659
28	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
29	rmd-1	T05G5.7	n/a	chrIII 9,759,548	C. elegans RMD-1 protein; contains similarity to Interpro domain IPR011990 (Tetratricopeptide-like helical)
30	F43G6.10	F43G6.10	n/a	chrII 11,809,738	contains similarity to Interpro domain IPR000694 (Proline-rich region)
31	C17F4.5	C17F4.5	n/a	chrII 3,247,215	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
32	tag-319	C30B5.1	n/a	chrII 6,200,135	C. elegans TAG-319 protein ;
33	C04B4.2	C04B4.2	n/a	chrX 12,284,223	contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
34	W03C9.2	W03C9.2	n/a	chrII 11,963,758	contains similarity to Schizosaccharomyces pombe Transcription elongation factor S-II (TFIIS).; SW:TFS2_SCHPO
35	R02F2.4	R02F2.4	n/a	chrIII 5,485,028	R02F2.4 encodes a protein with six chitin-binding peritrophin-A domains; R02F2.4 transcripts are enriched during oogenesis; like CEJ-1 and CPG-2, R02F2.4 might participate in eggshell synthesis and early embryonic development, and R02F2.4's multiple peritrophin-A domains might enable mechanical cross-linking of chitin; however, R02F2.4 has no obvious function in mass RNAi assays; while R02F2.4 is more closely similar to CPG-2 than CEJ-1, it may be less strongly expressed (since it has substantially fewer ESTs) and thus be less important in development.
36	W06D11.1	W06D11.1	n/a	chrX 12,294,462
37	lrr-1	F33G12.4	n/a	chrII 5,035,345	F33G12.4 encodes a leucine rich repeat-containing protein; loss of F33G12.4 activity via large-scale RNAi indicates that F33G12.4 is essential for embryonic and larval development.
38	H04M03.3	H04M03.3	n/a	chrIV 5,892,434	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
39	F41C6.3	F41C6.3	n/a	chrX 6,870,780
40	rnr-2	C03C10.3	n/a	chrIII 4,094,174	rnr-2 encodes the small subunit of ribonucleotide reductase; by homology, RNR-2 is predicted to function in deoxyribonucleotide biosynthesis; in C. elegans rnr-2 is an essential gene whose activity is required for reproduction and embryonic development.
41	F14D7.2	F14D7.2	n/a	chrV 14,292,817	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
42	kbp-1	R13F6.1	n/a	chrIII 6,869,906	C. elegans KBP-1 protein ;
43	cpar-1	F54C8.2	n/a	chrIII 9,434,486	cpar-1 encodes one of two C. elegans proteins homologous to the inner kinetochore histone H3 variant CENP-A (the other is encoded by hcp-3); loss of cpar-1 and hcp-3 activity via RNAi results in mitotic chromosome segregation defects, but no significant defects in meiotic chromosome segregation; when expressed in the germline using the pie-1 promoter, a CPAR-1::GFP fusion protein localizes to meiotic chromosomes during late prophase/prometaphase of meiosis I, but is not seen on chromosomes during meiosis II.
44	C27D9.1	C27D9.1	n/a	chrII 4,754,512	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
45	cdc-25.3	ZK637.11	n/a	chrIII 8,917,082	cdc-25.3 encodes a tyrosine phosphatase that is a member of the cell division cycle 25 (CDC25) family of cell cycle regulators that includes Schizosaccharomyces pombe CDC25 and Drosophila string; cdc-25.3 is one of four cdc-25 genes in C. elegans and while it is known to be expressed in hermaphrodites, the precise function of cdc-25.3 is not yet clear; cdc-25.3 may function redundantly with cdc-25.2 during embryonic development and redundantly with cdc-25.1, cdc-25.2, and emb-29 during meiosis.
46	rfc-3	C39E9.13	n/a	chrIV 13,096,350	C. elegans RFC-3 protein; contains similarity to Interpro domains IPR008921 (DNA polymerase III clamp loader subunit, C-terminal), IPR003593 (AAA+ ATPase, core)
47	F54F7.6	F54F7.6	n/a	chrX 11,866,107	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
48	C18A3.1	C18A3.1	n/a	chrII 5,720,938	contains similarity to Pfam domain PF05063 MT-A70 contains similarity to Interpro domains IPR007757 (MT-A70), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
49	msh-4	T02G5.6	n/a	chrII 7,078,297	C. elegans MSH-4 protein; contains similarity to Pfam domain PF00488 MutS domain V contains similarity to Interpro domain IPR000432 (DNA mismatch repair protein MutS, C-terminal)
50	R04D3.2	R04D3.2	n/a	chrX 13,285,808	contains similarity to Plasmodium falciparum Putative uncharacterized protein PFD0207c.; TR:Q8I1Y6