UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	B0361.6	B0361.6	0	chrIII 7,276,316	contains similarity to Pfam domain PF02598 Uncharacterized ACR, COG2106 contains similarity to Interpro domain IPR003750 (Protein of unknown function DUF171)
2	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	scc-3	F18E2.3	n/a	chrV 12,765,914	scc-3 encodes a cohesin complex subunit homologous to Saccharomyces cerevisiae Irr1p/Scc3p; SCC-3 is required during meiosis for synaptonemal complex formation and sister chromatid cohesion, proper localization of REC-8 to chromosomes, mitotic chromosome segregation, embryonic development, and vulval morphogenesis; in embryos, SCC-3 forms a cohesin complex with SCC-1, SMC-1, SMC-3, and TIM-1, a HEAT/Armadillo repeat-containing protein related to Drosophila TIMELESS; in the germline, SCC-3 associates with chromatin of transistion zone nuclei, assembles along the longitudinal axes of synapsed chromosomes at pachytene, and unlike other cohesins, localizes throughout chromatin at diakinesis; SCC-3 localization requires TIM-1, and SCC-3 and REC-8 are mutually required for chromatin localization.
5	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
6	R09B3.3	R09B3.3	n/a	chrI 11,910,664	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
7	cpg-4	C10F3.1	n/a	chrV 5,997,803	cpg-4 encodes a large (782-residue), unfamiliar, putatively secreted protein with a C-terminal low-complexity domain; CPG-4 has 35 potential chondroitin attachment sites, mostly in its C-terminal half, 4 of which have been verified by mass spectrometry; CPG-4 has no obvious function in mass RNAi assays.
8	srh-293	K08G2.8	n/a	chrV 15,866,710	C. elegans SRH-293 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	W09G10.3	W09G10.3	n/a	chrII 3,526,838	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
10	set-32	C41G7.4	n/a	chrI 9,520,403	set-32 encodes a divergent histone H3 lysine-9 (H3K9) methyltransferase homolog with a SET domain; SET-32 has no obvious non-nematode orthologs, but several paralogs (SET-6, SET-13, SET-15, SET-19, SET-20, and SET-21); set-32(ok1457) has no obvious mutant phenotype, and SET-32 has no obvious function in mass RNAi assays.
11	R09D1.2	R09D1.2	n/a	chrII 9,441,109	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
12	F10C2.4	F10C2.4	n/a	chrV 12,043,441	F10C2.4 encodes a homolog of the DNA polymerase delta complex subunit A that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and, also, for normal chromosome segregation (probably because of defective DNA replication).
13	K02D10.4	K02D10.4	n/a	chrIII 8,778,867
14	C16C10.2	C16C10.2	n/a	chrIII 4,178,135	contains similarity to Pfam domain PF03998 Utp11 protein contains similarity to Interpro domain IPR007144 (Small-subunit processome, Utp11)
15	C01G6.5	C01G6.5	n/a	chrII 9,277,455	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR005819 (Histone H5), IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000253 (Forkhead-associated), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
16	seld-1	Y45F10A.4	n/a	chrIV 13,507,532	C. elegans SELD-1 protein; contains similarity to Pfam domains PF02769 (AIR synthase related protein, C-terminal domain) , PF00586 (AIR synthase related protein, N-terminal domain) contains similarity to Interpro domains IPR016188 (PurM, N-terminal-like), IPR000728 (AIR synthase related protein), IPR010918 (AIR synthase related protein, C-terminal), IPR004536 (Selenide water dikinase)
17	T16G12.1	T16G12.1	n/a	chrIII 10,044,880	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR002355 (Multicopper oxidase, copper-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
18	ZK632.3	ZK632.3	n/a	chrIII 9,803,610	contains similarity to Pfam domain PF01163 RIO1 family contains similarity to Interpro domains IPR000687 (RIO kinase), IPR011009 (Protein kinase-like), IPR017406 (Serine/threonine-protein kinase Rio3)
19	srh-51	C10G11.3	n/a	chrI 6,301,375	C. elegans SRH-51 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	lgc-5	F17E9.7	n/a	chrIV 8,343,385	C. elegans LGC-5 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
21	T07G12.8	T07G12.8	n/a	chrIV 10,553,796	contains similarity to Thermoplasma volcanium ABC transport system permease protein P1P2A1A2.; TR:Q978R0
22	F43C9.2	F43C9.2	n/a	chrX 4,788,190	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
23	C07H6.2	C07H6.2	n/a	chrIII 7,521,145	contains similarity to Pfam domain PF07491 Protein phosphatase inhibitor contains similarity to Interpro domain IPR011107 (Protein phosphatase inhibitor)
24	H28G03.4	H28G03.4	n/a	chrX 5,223,420	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
25	srw-118	C44C3.5	n/a	chrV 2,979,418	C. elegans SRW-118 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
26	C01B7.5	C01B7.5	n/a	chrV 8,800,549	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
27	F26B1.5	F26B1.5	n/a	chrI 6,309,949	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
28	C06B3.2	C06B3.2	n/a	chrV 13,901,062	contains similarity to Pfam domain PF00350 Dynamin family contains similarity to Interpro domain IPR001401 (Dynamin, GTPase region)
29	F27C1.3	F27C1.3	n/a	chrI 5,426,839	contains similarity to Pfam domain PF03057 Protein of unknown function contains similarity to Interpro domains IPR004296 (Protein of unknown function DUF236), IPR002952 (Eggshell protein)
30	W07E6.3	W07E6.3	n/a	chrII 496,617	contains similarity to Interpro domain IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase)
31	K01D12.6	K01D12.6	n/a	chrV 12,399,785	contains similarity to Homo sapiens Isoform 1 of Protein FAM73B; ENSEMBL:ENSP00000351138
32	F09A5.2	F09A5.2	n/a	chrX 13,137,360	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
33	T03G6.3	T03G6.3	n/a	chrX 2,613,474	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
34	pdr-1	K08E3.7	n/a	chrIII 13,772,270	pdr-1 encodes an ortholog of human parkin (PARK2; OMIM:602544), which when mutated leads to the juvenile 2 form of Parkinson disease (OMIM:600116).
35	F52B11.2	F52B11.2	n/a	chrIV 14,084,140	F52B11.2 is orthologous to the human gene PHOSPHOMANNOMUTASE 2 (PMS2; OMIM:601785), which when mutated leads to congenital disorder of glycosylation, type Ia.
36	M03C11.3	M03C11.3	n/a	chrIII 10,409,775	contains similarity to Saccharomyces cerevisiae Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; SGD:YKL172W
37	T24F1.2	T24F1.2	n/a	chrII 11,304,196	contains similarity to Drosophila melanogaster Flybase gene name is CG7744-PA;; FLYBASE:CG7744
38	T12A2.6	T12A2.6	n/a	chrIII 6,243,060
39	F42C5.6	F42C5.6	n/a	chrIV 7,308,755
40	C06E1.9	C06E1.9	n/a	chrIII 8,608,051	contains similarity to Interpro domain IPR001680 (WD40 repeat)
41	C32E8.5	C32E8.5	n/a	chrI 3,782,660	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000253 (Forkhead-associated)
42	nsh-1	F20H11.2	n/a	chrIII 6,595,590	C. elegans NSH-1 protein; contains similarity to Pfam domain PF00271 Helicase conserved C-terminal domain contains similarity to Interpro domains IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
43	B0001.5	B0001.5	n/a	chrIV 12,142,216	contains similarity to Saccharomyces cerevisiae Gtpase-activating protein activity toward the essential bud-site assembly GTPase Cdc42; SGD:YPL115C
44	T07D1.5	T07D1.5	n/a	chrX 2,419,146
45	T22B11.5	T22B11.5	n/a	chrIV 4,700,455	The T22B11.5 gene encodes an ortholog of the human gene OGDH, which when mutated leads to alpha-ketoglutarate deficiency (OMIM:203740); the T22B11.5 protein is predicted to be mitochondrial with 68% accuracy.
46	kgb-1	T07A9.3	n/a	chrIV 407,854	kgb-1 encodes a serine/threonine kinase that is a member of the JNK (Jun-N-terminal kinase) subfamily of MAP (mitogen-activated protein)kinases; loss of kgb-1 activity results in temperature-sensitive sterility in hermaphrodites and males; in hermaphrodites, this sterility is associated with disorganized gonads and endomitotic oocytes that have likely failed to undergo oocyte maturation; in kgb-1 mutant males, sperm is present, but is non-functional; KGB-1 interacts in vitro with all four C. elegans germline helicases, GLH-1, -2, -3, and -4, that localize to P granules in vivo; Northern analyses indicate that kgb-1 mRNA is present in both somatic and germline tissues.
47	pes-7	F09C3.1	n/a	chrI 14,267,298	pes-7 encodes an IQGAP ortholog; IQGAP proteins bind actin and CLIP-170, effect activities of the Rho family GTPases Rac1 and Cdc42, and function in cytokinesis; PES-7 is required for completing meiosis and mitosis, and for germline formation and maintenance; IQGAP's alpha-actinin domain is related distantly to alpha-actinin domains in calponin, transgelin (SM22 alpha), and the proto-oncogene Vav; a pes-7 reporter is first expressed in the ventral nerve cord of the elongating embryo and in later stages of development is also expressed in all major ganglia, the vulva, and in the spermathecal valves; in the ventral nerve cord, pes-7 expression is detected in nuclei as well as in cell bodies and neural processes.
48	vha-1	R10E11.8	n/a	chrIII 9,781,407	vha-1 encodes an ortholog of subunit c of the membrane-bound (V0) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-1 is a predicted V-ATPase transmembrane rotor component; VHA-1 and VHA-2/3 comprise a closely related family of subunit c co-orthologs, predicted to carry protons from the cytosol to a-subunits (VHA-5, VHA-6, VHA-7, or UNC-32) for transmembrane export; VHA-1, like VHA-12 and VHA-17, antagonizes EFF-1-mediated cell fusion in hypodermal cells; VHA-1 is required for ovulation and embryogenesis, since vha-1(RNAi) animals are sterile with polyploid, unmatured oocytes and dead progeny; VHA-1 is required for alae formation, like the V0 subunits VHA-4 and VHA-5, but not like the V1 subunits VHA-8 or VHA-13; vha-1 shares an operon with vha-2 and R10E11.6; both vha-1 and vha-2 are expressed in the excretory cell, the rectum, and a pair of cells near the anus.
49	W06H3.3	W06H3.3	n/a	chrV 16,798,543	contains similarity to Pfam domains PF00117 (Glutamine amidotransferase class-I) , PF06418 (CTP synthase N-terminus) contains similarity to Interpro domains IPR000630 (Ribosomal protein S8), IPR017456 (CTP synthase, N-terminal), IPR000991 (Glutamine amidotransferase class-I, C-terminal), IPR004468 (CTP synthase), IPR012998 (Glutamine amidotransferase, class I, active site)
50	sdc-3	C25D7.3	n/a	chrV 15,043,550	sdc-3 encodes a protein that contains two mutationally separable domains: a zinc finger motif required for dosage compensation and a myosin- like putative ATP- binding region required for her-1 regulation of sex determination; SDC-3 activates dosage compensation by directing the dosage compensation protein complex to the hermaphrodite X chromosomes, and is functionally redundant with SDC-2 with respect to dosage compensation; SDC-1, SDC-2, and SDC-3 proteins form a complex.