UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nlp-31	B0213.6	0.004	chrV 3,980,323	nlp-31 encodes five predicted neuropeptide-like proteins; in C. elegans, nlp-31 is part of the YGGWamide neuropeptide family that also contains nlp-24, nlp-25, and nlp-27-32; nlp-31 is expressed in the hypodermis, suggesting that the peptides it encodes may have a non-neuronal function; nlp-31 expression is also detected in precomma-stage embryos; as loss of nlp-31 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-31-encoded peptides in development and/or behavior is not yet known.
2	F47B8.4	F47B8.4	n/a	chrV 14,324,002	contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR012336 (Thioredoxin-like fold)
3	K01A2.10	K01A2.10	n/a	chrII 322,278	contains similarity to Homo sapiens Coiled-coil domain-containing protein 92; ENSEMBL:ENSP00000238156
4	C14A6.2	C14A6.2	n/a	chrV 18,151,568	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
5	T10G3.1	T10G3.1	n/a	chrV 13,471,322	contains similarity to Saccharomyces cerevisiae interacts with Sin1p; SGD:YER047C
6	K02A6.2	K02A6.2	n/a	chrX 8,224,536
7	T07D1.3	T07D1.3	n/a	chrX 2,443,181	contains similarity to Interpro domain IPR016160 (Aldehyde dehydrogenase, conserved site)
8	ZC443.2	ZC443.2	n/a	chrV 12,810,803	contains similarity to Listeria innocua Hypothetical protein lin2372.; TR:Q929A5
9	ins-11	C17C3.4	n/a	chrII 5,556,897	ins-11 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-11 is one of 38 insulin-like peptides in C. elegans and is expressed in the labial sensory neurons, the nerve ring, and other neurons; although the precise role of INS-11 in C. elegans development is not yet clear, loss of INS-11 function via RNA-mediated interference can result in animals that are smaller than wild type (Sma).
10	flp-24	C24A1.1	n/a	chrIII 725,550	C. elegans FLP-24 protein ;
11	grd-9	C04E6.6	n/a	chrV 5,896,978	grd-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-9 is weakly required for normal molting; GRD-9 is also required for normal growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
12	T28A11.5	T28A11.5	n/a	chrV 3,270,895	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR003559 (Cytolethal distending toxin C), IPR002542 (Protein of unknown function DUF19)
13	fbxa-164	C08E3.7	n/a	chrII 1,613,450	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
14	zig-3	C14F5.2	n/a	chrX 7,931,218	zig-3 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-3::gfp reporter fusion is expressed in the PVT, AIM, and ASI neurons, as well as in the vulva and weakly in the body wall muscle.
15	nlp-30	B0213.5	n/a	chrV 3,982,348	nlp-30 encodes five predicted neuropeptide-like proteins; in C. elegans, nlp-30 is part of the YGGWamide neuropeptide family that also contains nlp-24, nlp-25, and nlp-27-32; nlp-30 is expressed in the hypodermis, suggesting that the peptides it encodes may have a non-neuronal function; as loss of nlp-30 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-30-encoded peptides in development and/or behavior is not yet known.
16	F53F4.7	F53F4.7	n/a	chrV 13,613,185	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
17	F47B8.2	F47B8.2	n/a	chrV 14,316,299	contains similarity to Lyngbya lagerheimii CP 43 protein (Fragment).; TR:Q937F7
18	tsp-5	Y45F10B.1	n/a	chrIV 13,591,144	C. elegans TSP-5 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
19	lact-6	C06A12.5	n/a	chrIV 17,430,817	lact-6 encodes a beta-lactamase domain-containing protein that contains a predicted signal sequence in its N terminus.
20	nlp-37	F48B9.4	n/a	chrX 2,163,570	C. elegans NLP-37 protein ;
21	C07A9.8	C07A9.8	n/a	chrIII 9,688,522	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
22	C17G10.7	C17G10.7	n/a	chrII 5,607,281
23	T27E4.1	T27E4.1	n/a	chrV 9,093,497	contains similarity to Interpro domain IPR008973 (C2 calcium/lipid-binding region, CaLB)
24	cyp-13A3	T10B9.5	n/a	chrII 9,791,013	C. elegans CYP-13A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
25	tyr-3	F21C3.2	n/a	chrI 7,276,425	C. elegans TYR-3 protein; contains similarity to Pfam domains PF00264 (Common central domain of tyrosinase) , PF01549 (ShK domain-like) (4)contains similarity to Interpro domains IPR008922 (Di-copper centre-containing), IPR002227 (Tyrosinase), IPR003582 (Metridin-like ShK toxin)
26	ttr-29	R90.4	n/a	chrV 12,906,429	C. elegans TTR-29 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
27	tsp-4	F53B2.2	n/a	chrIV 12,519,672	C. elegans TSP-4 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
28	nlp-5	F35C11.1	n/a	chrII 8,243,059	C. elegans NLP-5 protein ;
29	F11C1.4	F11C1.4	n/a	chrX 12,979,059	contains similarity to Drosophila melanogaster Flybase gene name is CG9186-PA;; FLYBASE:CG9186
30	Y38H6C.19	Y38H6C.19	n/a	chrV 20,548,064	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
31	F08H9.3	F08H9.3	n/a	chrV 14,462,384	F08H9.3 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the larval pharynx and the anterior adult pharynx), and its expression is not strongly induced by heat shock; however, F08H9.3 expression is increased by heat shock (with adult expression in the full pharynx) and probably aids heat shock resistance, since F08H9.3(RNAi) animals have sensitivity to heat shock that is sporadically higher than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.
32	T23G7.3	T23G7.3	n/a	chrII 9,166,799	contains similarity to Pfam domain PF01585 G-patch domain contains similarity to Interpro domain IPR000467 (D111/G-patch)
33	fbxa-24	F54D10.2	n/a	chrII 3,817,370	C. elegans FBXA-24 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
34	gst-41	R13D7.7	n/a	chrV 7,398,864	C. elegans GST-41 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
35	srbc-20	C45H4.11	n/a	chrV 2,147,858	C. elegans SRBC-20 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
36	dhs-26	ZK816.5	n/a	chrX 3,361,621	dhs-26 encodes a short-chain dehydrogenase predicted to be mitochondrial.
37	nhr-260	C38C3.9	n/a	chrV 1,510,828	C. elegans NHR-260 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
38	K01D12.10	K01D12.10	n/a	chrV 12,406,600	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR003072 (Orphan nuclear receptor, NOR1 type), IPR003982 (Leukotriene B4 type 2 receptor)
39	T26G10.5	T26G10.5	n/a	chrIII 9,426,015	contains similarity to Streptococcus pyogenes Hypothetical protein SPy0952.; TR:Q9A032
40	F58B4.3	F58B4.3	n/a	chrV 10,930,269	contains similarity to Homo sapiens similar to bA88M19.1 (EGF-like-domain multiple 5 protein); ENSEMBL:ENSP00000223618
41	F18G5.6	F18G5.6	n/a	chrX 9,263,128
42	F08G12.8	F08G12.8	n/a	chrX 11,317,416	contains similarity to Mus musculus Tenascin-R.; TR:Q8BYI9
43	gbh-2	M05D6.7	n/a	chrII 8,486,654	gbh-2 encodes an ortholog of human gamma butyrobetaine hydroxilase 2 involved in carnitine biosynthesis; RNA interference of gbh-2 results in malformation of the gonad and accumulation of fat in the pseudocoelomic cavity and in intestinal cells; the GBH-2-GFP fusion protein is predominantly expressed in intestinal cells from early embryogenesis.
44	K09D9.9	K09D9.9	n/a	chrV 3,993,382
45	C08E8.4	C08E8.4	n/a	chrV 18,372,276	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
46	fbxa-161	C08E3.4	n/a	chrII 1,607,102	C. elegans FBXA-161 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
47	C32H11.3	C32H11.3	n/a	chrIV 12,919,384	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
48	T12A2.5	T12A2.5	n/a	chrIII 6,236,471
49	srj-24	C05E4.11	n/a	chrV 737,838	C. elegans SRJ-24 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
50	tag-243	T04A8.4	n/a	chrIII 4,686,618	C. elegans TAG-243 protein; contains similarity to Interpro domain IPR000637 (HMG-I and HMG-Y, DNA-binding)