UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	B0035.6	B0035.6	0	chrIV 11,322,187	contains similarity to Saccharomyces cerevisiae Structural maintenance of chromosomes (SMC) protein; SGD:YOL034W
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	Y62H9A.11	Y62H9A.11	n/a	chrX 11,906,196
4	Y53C12A.3	Y53C12A.3	n/a	chrII 9,705,022	contains similarity to Pfam domains PF03942 (DTW domain) , PF04893 (Yip1 domain) contains similarity to Interpro domains IPR006977 (Yip1 domain), IPR005636 (DTW)
5	sel-12	F35H12.3	n/a	chrX 917,054	sel-12 encodes a transmembrane domain protein orthologous to presenilins; during gonadal, germline, and vulval development, sel-12 functions, within receiving cells, to positively regulate lin-12 and glp-1 Notch-like signaling pathways; sel-12 presenilin activity and/or levels are likely regulated by the SET/NAP protein sub-family member encoded by spr-2, as mutations in sel-12 are suppressed by mutations in spr-2; spr-2 regulation of sel-12 occurs in a hop-1 presenilin dependent manner.
6	srx-22	F31F4.3	n/a	chrV 680,688	C. elegans SRX-22 protein ;
7	sri-6	T09E8.5	n/a	chrV 13,186,537	C. elegans SRI-6 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	srj-10	F14H3.1	n/a	chrV 16,073,333	C. elegans SRJ-10 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	lgc-7	Y57G11C.2	n/a	chrIV 14,712,127	C. elegans LGC-7 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
10	ZK177.9	ZK177.9	n/a	chrII 5,517,477
11	H14E04.4	H14E04.4	n/a	chrIII 2,391,147
12	B0035.16	B0035.16	n/a	chrIV 11,295,988	contains similarity to Pfam domain PF03054 tRNA methyl transferase contains similarity to Interpro domains IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004506 (tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase)
13	srh-72	ZC204.5	n/a	chrII 1,639,907	C. elegans SRH-72 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	srd-17	Y2H9A.2	n/a	chrV 13,431,663	C. elegans SRD-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	grd-10	F09D12.1	n/a	chrIV 3,441,427	grd-10 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; GRD-10 is expressed in seam cells; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-10 is weakly required for normal molting; GRD-10 is also required for normal growth to full size and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
16	srw-98	K04F1.3	n/a	chrV 1,677,402	C. elegans SRW-98 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
17	C01F6.1	C01F6.1	n/a	chrIV 9,098,665	C01F6.1 encodes a putative calcium-dependent phospholipid binding protein of the copine family; C01F6.1 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; C01F6.1(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
18	C34D4.10	C34D4.10	n/a	chrIV 7,120,692
19	W04G3.2	W04G3.2	n/a	chrX 11,063,262	contains similarity to Saccharomyces cerevisiae Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes; SGD:YGR097W
20	F56H6.4	F56H6.4	n/a	chrI 12,291,320	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
21	T25G12.2	T25G12.2	n/a	chrX 17,245,951	The T25G12.2 gene encodes a homolog of the human gene HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030); T25G12.2 protein is predicted to be mitochondrial with 68% accuracy.
22	Y40H7A.3	Y40H7A.3	n/a	chrIV 15,162,987	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
23	F21A3.5	F21A3.5	n/a	chrV 15,540,560	contains similarity to Pfam domain PF01966 HD domain contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR006674 (Metal-dependent phosphohydrolase, HD region, subdomain)
24	srh-82	W03F9.6	n/a	chrV 146,062	C. elegans SRH-82 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	C08E3.13	C08E3.13	n/a	chrII 1,632,158	C08E3.13 encodes a novel protein; expression studies indicate that C08E3.13 expression is positively regulated by signaling through the DBL-1/TGF-beta signaling pathway; in situ hybridization experiments reveal that C08E3.13 transcripts are expressed in the intestine and the vulva.
26	Y57G11C.7	Y57G11C.7	n/a	chrIV 14,755,336	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
27	K03D7.8	K03D7.8	n/a	chrV 17,490,522
28	btb-3	B0047.2	n/a	chrII 2,043,575	C. elegans BTB-3 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
29	srw-142	H05B21.3	n/a	chrV 2,957,658	C. elegans SRW-142 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	srd-50	F15A2.4	n/a	chrX 13,480,135	C. elegans SRD-50 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	Y18D10A.16	Y18D10A.16	n/a	chrI 12,903,539	contains similarity to Homo sapiens Uncharacterized protein C2orf64; ENSEMBL:ENSP00000330730
32	C33H5.1	C33H5.1	n/a	chrIV 7,809,904	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
33	T22H2.4	T22H2.4	n/a	chrI 11,694,849	contains similarity to Pfam domain PF03860 Domain of Unknown Function (DUF326) contains similarity to Interpro domain IPR005560 (Protein of unknown function DUF326)
34	sre-29	F57G9.4	n/a	chrII 12,400,560	C. elegans SRE-29 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
35	W01C8.1	W01C8.1	n/a	chrX 5,693,921
36	Y75B8A.7	Y75B8A.7	n/a	chrIII 12,156,145	contains similarity to Pfam domain PF04006 Mpp10 protein contains similarity to Interpro domains IPR012173 (U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p), IPR007151 (Mpp10 protein)
37	K09A9.4	K09A9.4	n/a	chrX 15,593,283	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domain IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
38	str-112	F10D2.4	n/a	chrV 7,137,353	C. elegans STR-112 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	D1007.8	D1007.8	n/a	chrI 4,604,894	contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold)
40	W06A11.1	W06A11.1	n/a	chrII 4,068,658
41	T09B4.2	T09B4.2	n/a	chrI 6,184,694
42	AH10.4	AH10.4	n/a	chrV 14,137,472	contains similarity to Methanosarcina acetivorans Hypothetical protein MA1935.; TR:Q8TPH7
43	clec-50	W04E12.8	n/a	chrV 19,749,271	C. elegans CLEC-50 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR000480 (Glutelin), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
44	ape-1	F46F3.4	n/a	chrV 11,680,585	ape-1 encodes an ortholog of inhibitory p53-interacting protein (iASPP); APE-1 binds CEP-1 in vitro, and shares 38% amino-acid identity in its ankyrin repeats and SH3 domain to iASPP, with many iASPP residues contacting p53 being conserved; RNAi of ape-1 induces CEP-1- and HUS-1-dependent apoptosis in the germline, consistent with inhibition of the CEP-1/HUS-1 DNA damage checkpoint by APE-1 in the germline; excess ape-1(RNAi) apoptosis also requires CED-3.
45	F55D12.2	F55D12.2	n/a	chrI 7,892,099	contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal)
46	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)
47	unc-8	R13A1.4	n/a	chrIV 7,200,978	unc-8 encodes an amiloride-sensitive DEG/ENaC cation-selective channel subunit orthologous to human ENaCB (OMIM:600760, associated with Liddle syndrome, an autosomal dominant form of hypertension); UNC-8 is predicted to function as part of a mechanically gated channel that responds to stretch, and is required for modulating the sinusoidal body wave that is characteristic of C. elegans locomotion; unc-8 interacts genetically with unc-1 and unc-24, which encode stomatin-like proteins, and with mec-6, which encodes a paraoxonase; UNC-8 is expressed in motor neurons, sensory neurons, and interneurons in the nerve ring; UNC-8 may form a channel with the degenerin DEL-1, with which it is coexpressed in ventral cord motor neurons.
48	srxa-9	ZK678.4	n/a	chrX 15,749,493	C. elegans SRXA-9 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
49	vps-35	F59G1.3	n/a	chrII 5,909,476	C. elegans VPS-35 protein; contains similarity to Pfam domain PF03635 Vacuolar protein sorting-associated protein 35 contains similarity to Interpro domain IPR005378 (Vacuolar protein sorting-associated protein 35)
50	T08D2.8	T08D2.8	n/a	chrX 196,174	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)