UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxb-59	Y113G7B.8	1e-154	chrV 20,200,762	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
2	smf-2	K11G12.3	n/a	chrX 6,717,366	C. elegans SMF-2 protein; contains similarity to Pfam domain PF01566 Natural resistance-associated macrophage protein contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)
3	Y116A8C.15	Y116A8C.15	n/a	chrIV 16,996,337	contains similarity to Homo sapiens similar to KIAA1357 protein; ENSEMBL:ENSP00000258005
4	fbxb-44	K05F6.5	0.0001	chrII 1,539,392	K05F6.5 encodes an unusual paraoxonase-like protein with an N-terminal F-box domain; it is homologous to the human PARAOXONASE 1 gene (PON1, OMIM:168820), which in some allelic forms is associated with susceptibility to coronary artery disease.
5	srh-136	F36D3.6	n/a	chrV 16,496,767	C. elegans SRH-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	apc-11	F35G12.9	n/a	chrIII 4,594,070	apc-11 encodes a predicted key catalytic subunit of the anaphase promoting complex that is required for embryonic development past the embryonic one- cell stage.
7	K09B11.4	K09B11.4	n/a	chrIV 13,429,722	contains similarity to Patella vulgata Twist protein (Fragment).; TR:Q8WQQ8
8	tbx-31	C36C9.2	n/a	chrX 1,672,652	tbx-31 encodes a diverged member of the T-box transcription factor family; by homology, TBX-31 is predicted to function as a transcriptional regulator during development, but as loss of tbx-31 activity via RNAi results in no obvious defects, the precise role of TBX-31 in C. elegans development and/or behavior is not yet known.
9	ZC53.4	ZC53.4	n/a	chrX 1,931,714	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227Y0
10	C09G9.3	C09G9.3	n/a	chrIV 8,871,534	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
11	fbxa-112	Y102A5C.13	n/a	chrV 16,947,523	C. elegans FBXA-112 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
12	F55E10.5	F55E10.5	n/a	chrX 8,335,538
13	sru-4	C33A12.10	n/a	chrIV 9,498,965	C. elegans SRU-4 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
14	srd-56	E04F6.14	n/a	chrII 7,202,553	C. elegans SRD-56 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	D1007.9	D1007.9	n/a	chrI 4,591,009
16	sru-19	T04A11.8	n/a	chrIV 12,499,445	C. elegans SRU-19 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
17	F15A4.5	F15A4.5	n/a	chrII 12,470,242	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ICX2
18	Y56A3A.11	Y56A3A.11	n/a	chrIII 11,896,407	contains similarity to Pfam domain PF01974 tRNA intron endonuclease, catalytic C-terminal domain contains similarity to Interpro domains IPR006677 (tRNA intron endonuclease, catalytic domain-like), IPR011856 (Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)
19	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
20	F08B4.3	F08B4.3	n/a	chrIV 8,666,337	contains similarity to Interpro domain IPR000719 (Protein kinase, core)
21	D1086.1	D1086.1	n/a	chrV 14,099,606	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
22	F56H6.11	F56H6.11	n/a	chrI 12,309,058	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
23	W02B8.1	W02B8.1	n/a	chrII 13,900,226
24	C37E2.3	C37E2.3	n/a	chrX 14,180,268	contains similarity to Pfam domain PF04750 FAR-17a/AIG1-like protein contains similarity to Interpro domains IPR006838 (FAR-17a/AIG1-like protein), IPR002208 (SecY protein)
25	C11H1.2	C11H1.2	n/a	chrX 14,306,277	contains similarity to Interpro domain IPR015672 (G-protein coupled receptor 89-related)
26	sas-5	F35B12.5	n/a	chrV 11,611,859	sas-5 encodes a coiled-coil protein whose activity is required, paternally, maternally, and in a dose-dependent manner, for daughter centriole formation; SAS-5 localizes to both the cytoplasm and to centrioles, and photobleaching experiments reveal rapid SAS-5 cycling between these two cellular components throughout the cell cycle; SAS-5 localization to centrioles depends upon the ZYG-1 kinase and the SAS-6 coiled-coil protein, two proteins also required for centriole duplication; in turn, SAS-5 activity is required for SAS-6 centriolar localization, as SAS-6 fails to localize properly in sas-5 mutant embryos.
27	clec-245	C31G12.2	n/a	chrV 18,187,150	C. elegans CLEC-245 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	K07D4.4	K07D4.4	n/a	chrII 4,032,008
29	C03B1.10	C03B1.10	n/a	chrX 6,357,809	contains similarity to Homo sapiens cDNA FLJ42885 fis, clone BRHIP3007586; HI:HIT000044748
30	tsg-101	C09G12.9	n/a	chrIV 3,512,510	C09G12.9 encodes the C. elegans ortholog of S. cerevisiae vacuolar protein sorting protein Vps23p and human TUMOR SUSCEPTIBILITY GENE 101 (TSG101; OMIM:601387), mutations in which are associated with several types of cancer and with varying responses to HIV infection; the product of C09G12.9 is predicted to be a component of C. elegans ESCRT-1 (Endosomal Sorting Complex Required for Transport), and RNAi experiments indicate that its activity is essential for embryonic and larval development.
31	nlp-13	E03D2.1	n/a	chrV 4,237,211	nlp-13 encodes a predicted neuropeptide of the MSFamide family; expressed primarily in neurons or in the endocrine/secretory cells, and expression includes pharyngeal neurons that modulate pharyngeal pumping of food.
32	C18G1.7	C18G1.7	n/a	chrV 4,746,815	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR008166 (Protein of unknown function DUF23)
33	C07A9.12	C07A9.12	n/a	chrIII 9,726,313	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
34	R11G11.3	R11G11.3	n/a	chrV 531,412	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
35	cdh-4	F25F2.2	n/a	chrIII 4,528,691	A homolog of a member of the cadherin superfamily that is involved in cell-cell adhesion.
36	ceh-1	F16H11.4	n/a	chrX 4,653,768	ceh-1 encodes a protein that contains a homeobox domain.
37	C24A3.1	C24A3.1	n/a	chrX 9,003,584	contains similarity to Aedes aegypti Condensin, SMC5-subunit, putative (Fragment).; TR:Q16IF0
38	Y45F3A.5	Y45F3A.5	n/a	chrIII 10,585,998	contains similarity to Saccharomyces cerevisiae Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; SGD:YOR310C
39	ZC373.5	ZC373.5	n/a	chrX 10,073,415	contains similarity to Pfam domain PF00596 Class II Aldolase and Adducin N-terminal domain contains similarity to Interpro domain IPR001303 (Class II aldolase/adducin, N-terminal)
40	trx-2	B0024.9	n/a	chrV 10,314,942	C. elegans TRX-2 protein; contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012335 (Thioredoxin fold), IPR015467 (Thioredoxin family), IPR001200 (Phosducin), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related), IPR012336 (Thioredoxin-like fold)
41	C31E10.1	C31E10.1	n/a	chrX 13,985,013	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000238 (Ribosome-binding factor A)
42	F45F2.7	F45F2.7	n/a	chrV 8,523,135	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR004878 (Protein of unknown function DUF270), IPR016196 (MFS general substrate transporter)
43	K02D7.2	K02D7.2	n/a	chrIV 312,624	K02D7.2 encodes an ortholog of human SNAI2/SLUG (OMIM:602150, mutated in Waardenburg syndrome type IID) and Drosophila ESCARGOT; based on its orthology to SNAI2, K02D7.2 is predicted to be a transcriptional inhibitor.
44	Y49F6C.8	Y49F6C.8	n/a	chrII 3,369,682
45	athp-1	C44B9.4	n/a	chrIII 10,887,899	C. elegans ATHP-1 protein; contains similarity to Pfam domains PF02178 (AT hook motif) (2), PF00628 (PHD-finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region), IPR000253 (Forkhead-associated), IPR011011 (Zinc finger, FYVE/PHD-type)
46	phat-1	C46H11.8	n/a	chrI 5,045,010	C. elegans PHAT-1 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
47	ztf-8	ZC395.8	n/a	chrIII 5,271,035	C. elegans ZTF-8 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR004355 (Type IV secretion system CagA exotoxin), IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
48	F02E11.4	F02E11.4	n/a	chrII 3,276,774	contains similarity to Interpro domain IPR002625 (Smr protein/MutS2 C-terminal)
49	E04F6.10	E04F6.10	n/a	chrII 7,215,446
50	evl-20	F22B5.1	n/a	chrII 8,444,637	evl-20 encodes a functional ortholog of human ADP-ribosylation factor-like protein 2 (ARL2; OMIM:601175), with evl-20(ar103) mutants being rescued by transgenic human ARL2 but not ARL1 or ARL3-7; EVL-20 is required for cortical microtubule formation during cytokinesis and morphogenesis; EVL-20 is required for vulval, gonadal, and male tail development, as well as for embryonic mitosis, hypodermal enclosure, and elongation; EVL-20 is expressed in migrating hypodermal embryonic cells, larval vulval and somatic gonad cells, larval and adult neurons, and adult male proctodeal cells, being subcellularly associated with both the cell cortex and astral microtubules.