UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F46F11.7	F46F11.7	0	chrI 5,621,853	contains similarity to Interpro domain IPR011061 (Proteinase inhibitor I14/I15, hirudin/antistatin)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F56D5.5	F56D5.5	n/a	chrIV 9,407,671	contains similarity to Interpro domain IPR000533 (Tropomyosin)
4	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
5	C30A5.6	C30A5.6	n/a	chrIII 8,206,270
6	ZC373.5	ZC373.5	n/a	chrX 10,073,415	contains similarity to Pfam domain PF00596 Class II Aldolase and Adducin N-terminal domain contains similarity to Interpro domain IPR001303 (Class II aldolase/adducin, N-terminal)
7	ceh-34	C10G8.6	n/a	chrV 5,317,530	ceh-34 encodes a homeodomain protein, homologous to human SIX2 (OMIM:604994), that is expressed very weakly in the pharynxes of late embryos and early larvae; it has no known function.
8	cyp-23A1	B0304.3	n/a	chrII 4,514,151	The B0304.3 gene encodes a homolog of the human gene CYP7B1, which when mutated leads to giant cell hepatitis (OMIM:231100).
9	chd-3	T14G8.1	n/a	chrX 12,849,438	chd-3 encodes a PHD-finger SNF2 family member containing a chromo domain and a C-terminal helicase domain that affects Notch-dependent vulval development; expressed in virtually all embryonic cells and in many larval nuclei.
10	soc-1	F41F3.2	n/a	chrV 4,644,923	C. elegans SOC-1 protein; contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type)
11	F15A4.5	F15A4.5	n/a	chrII 12,470,242	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ICX2
12	F40G12.6	F40G12.6	n/a	chrV 14,272,120	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
13	fbxa-52	F07G6.6	n/a	chrX 1,710,748	C. elegans FBXA-52 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
14	F57B7.2	F57B7.2	n/a	chrV 11,442,786	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
15	cdk-2	K03E5.3	n/a	chrI 3,411,552	C. elegans CDK-2 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
16	unc-122	F11C3.2	n/a	chrI 14,873,757	unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known.
17	F22F1.3	F22F1.3	n/a	chrX 8,162,399	contains similarity to Pfam domain PF02172 KIX domain contains similarity to Interpro domain IPR003101 (Coactivator CBP, KIX)
18	ZK1086.2	ZK1086.2	n/a	chrX 13,792,979	contains similarity to Shewanella oneidensis Hypothetical protein.; TR:Q8EJA6
19	F52D1.2	F52D1.2	n/a	chrX 447,631
20	srh-15	C50B6.6	n/a	chrV 13,321,651	C. elegans SRH-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	F38B6.6	F38B6.6	n/a	chrX 6,687,229	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (4), PF08409 (Domain of unknown function (DUF1736)) , PF00515 (Tetratricopeptide repeat) (5)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013618 (Region of unknown function DUF1736), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
22	F53B3.2	F53B3.2	n/a	chrX 2,860,247	contains similarity to Pfam domain PF01596 O-methyltransferase contains similarity to Interpro domain IPR002935 (O-methyltransferase, family 3)
23	nhr-176	F14H3.11	n/a	chrV 16,072,040	C. elegans NHR-176 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	unc-130	C47G2.2	n/a	chrII 11,282,880	A member of the forkhead domain family of transcription factors that affects the generation of the AWA and ASG chemosensory neurons and is partially required for male tail morphogenesis and embryogenesis; it is expressed in the AWA and ASG precursors; it is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor.
25	C49H3.9	C49H3.9	n/a	chrIV 7,908,266	contains similarity to Pfam domain PF07967 C3HC zinc finger-like contains similarity to Interpro domain IPR012935 (Zinc finger, C3HC-like)
26	F11A5.6	F11A5.6	n/a	chrV 16,203,986	contains similarity to Bradyrhizobium japonicum Bll7368 protein.; TR:Q89DS1
27	unc-50	T07A5.2	n/a	chrIII 10,316,260	unc-50 encodes an integral membrane protein orthologous to the Saccharomyces cerevisiae Golgi component Gmh1p; UNC-50 is required for regulating subtype-specific nicotinic receptor trafficking to the cell surface and thus, for normal synaptic transmission at the neuromuscular junction; UNC-50 is ubiquitously expressed from early embryogenesis to adulthood and localizes to the Golgi.
28	kal-1	K03D10.1	n/a	chrI 14,135,394	kal-1 encodes a cell surface protein that contains a WAP-type protease inhibitor domain and Type III fibronectin domains and is the C. elegans ortholog of human KAL-1, mutated in the X-linked form of the neurological disorder Kallmann syndrome; in C. elegans, both kal-1 loss-of-function mutations and kal-1 overexpression result in similar phenotypes that indicate KAL-1 activity is required for epithelial morphogenesis and axon branching; kal-1 transcriptional reporters reveal expression beginning in the 50-cell stage embryo in 2-3 cells with later embryonic expression in at least 8-10 AB-derived ventral neuroblasts that are a substrate for migrating epidermal cells during ventral enclosure; later expression in larvae and adults is restricted to anterior neurons, including AIY, AIZ, RID, M5, ASI, and labial sensory neurons, ventral nerve cord motorneurons, midbody neurons HSN, CAN, and PVM, tail neurons DVB, DVC, and PDB, and the nonneuronal excretory cell as well as in uterine muscles; in the AIY interneurons, kal-1 is part of a gene battery whose expression is under the control of the CEH-10 and TTX-3 Paired and LIM-type homeodomains, respectively.
29	K08C9.5	K08C9.5	n/a	chrI 11,483,971	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
30	F21F3.2	F21F3.2	n/a	chrI 4,904,288	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
31	T07F12.3	T07F12.3	n/a	chrX 4,887,726	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
32	unc-97	F14D12.2	n/a	chrX 5,593,799	The unc-97 gene encodes a LIM domain-containing protein of the PINCH family that is highly similar to human LIMS1 (OMIM:602567) and LIMS2; UNC-97 functions as an adaptor protein important for assembly of muscle adherens junctions and the mechanosensory functions of the touch neurons; UNC-97 interacts with PAT-4/integrin-linked kinase and with UNC-98; UNC-97 colocalizes with PAT-3/beta integrin at dense bodies, focal adhesion-like muscle attachment structures.
33	ZC513.1	ZC513.1	n/a	chrV 8,056,969	contains similarity to Pfam domain PF02886 LBP / BPI / CETP family, C-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
34	K02D3.2	K02D3.2	n/a	chrX 13,710,264	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
35	tor-2	Y37A1B.13	n/a	chrIV 13,983,393	tor-2 encodes a AAA ATPase that, along with TOR-1 and OOC-5, comprise the three C. elegans orthologs of human torsinA, mutations in which are associated with torsion dystonia (OMIM:605204); overexpression of TOR-2 in nematodes with polyglutamine repeat-induced protein aggregates indicates that TOR-2 can suppress protein aggregation, suggesting TOR-2 may play a role in regulation of protein folding; in wild-type animals, TOR-2 localizes to the endoplasmic reticulum; in animals containing polyglutamine protein aggregates, TOR-2 localizes to these sites of protein aggregation.
36	W01C9.1	W01C9.1	n/a	chrII 8,533,713	contains similarity to Brugia pahangi Heat shock protein 90.; SW:HS90_BRUPA
37	srv-11	H25K10.3	n/a	chrIV 16,220,615	C. elegans SRV-11 protein; contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002651 (Protein of unknown function DUF32)
38	sor-3	C04E7.2	n/a	chrX 355,777	sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins; during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size; SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons; in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway; sor-3 and sop-2 also function together to regulate progression through larval development; a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus.
39	B0399.2	B0399.2	n/a	chrV 19,551,938	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
40	R10E12.2	R10E12.2	n/a	chrIII 9,968,408	contains similarity to Homo sapiens Splice isoform 1 of Q96PV0 Ras GTPase-activating protein SynGAP; ENSEMBL:ENSP00000293748
41	tag-224	B0496.8	n/a	chrIV 7,450,248	tag-224 encodes an ortholog of Drosophila CG6522-PA and of human LMCD1 and TESTIN; TAG-224 is dispensable for Wnt-directed planar cell polarity and the fully asymmetrical division of B.a versus B.p cells.
42	gcy-3	R134.1	n/a	chrII 9,504,941	gcy-3 is predicted to encode a guanylate cyclase.
43	R07B1.9	R07B1.9	n/a	chrX 9,879,387	contains similarity to Arabidopsis thaliana Hypothetical protein (At1g15170).; TR:Q8L731
44	T08G2.2	T08G2.2	n/a	chrX 17,207,313	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
45	btb-12	ZC204.3	n/a	chrII 1,655,685	C. elegans BTB-12 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
46	R07C12.2	R07C12.2	n/a	chrIV 4,149,092
47	AC8.7	AC8.7	n/a	chrX 230,898
48	osm-10	T20H4.1	n/a	chrIII 7,244,451	osm-10 encodes a novel protein conserved amongst several Caenorhabditis species; osm-10 activity is required for normal osmosensory signaling in the ASH sensory neuron; in regulating ASH-mediated osmosensation, osm-10 interacts genetically with eos-1 and eos-2; OSM-10 is expressed in the ASH, ASI, PHA, and PHB sensory neurons beginning just prior to hatching and continuing through larval and adult stages; OSM-10 localizes to cell bodies, sensory processes, and axons.
49	T22C8.3	T22C8.3	n/a	chrII 8,621,191	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
50	clec-182	C33D9.2	n/a	chrIV 8,797,600	C. elegans CLEC-182 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)