UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	aos-1	C08B6.9	0	chrV 10,128,881	aos-1 encodes the C. elegans ortholog of Saccharomyces cerevisiae Aos1p and human SUMO-1 activating enzyme E1 N subunit; by homology, AOS-1 is predicted to form, with a catalytic subunit, UBA-2, a heterodimeric enzyme that activates the ubiquitin-like protein SMO-1/SUMO in preparation for its covalent attachment to target proteins to regulate their subcellular localization and/or stability; in C. elegans, AOS-1 is required for embryonic and larval development, as well as for proper Hox gene regulation; uba-2/aos-1(RNAi) animals that survive embryogenesis show ectopic expression of EGL-5 and ectopic anterior sensory ray formation.
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	nas-27	T23F4.4	n/a	chrII 1,177,703	nas-27 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-27::GFP promoter fusion is expressed in the reproductive system, the vulva, and the hypodermis.
4	T08A11.1	T08A11.1	n/a	chrIII 4,255,571	contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR000591 (Pleckstrin/ G-protein, interacting region)
5	F19F10.8	F19F10.8	n/a	chrV 7,570,024
6	C45G9.5	C45G9.5	n/a	chrIII 5,049,097
7	W09C3.4	W09C3.4	n/a	chrI 4,705,213	contains similarity to Pfam domain PF05158 RNA polymerase Rpc34 subunit contains similarity to Interpro domains IPR016049 (RNA polymerase Rpc34-like), IPR007832 (RNA polymerase Rpc34)
8	W02D3.4	W02D3.4	n/a	chrI 6,720,208	contains similarity to Pfam domain PF07857 CEO family (DUF1632) contains similarity to Interpro domain IPR012435 (Protein of unknown function DUF1632)
9	F44B9.5	F44B9.5	n/a	chrIII 8,015,142	contains similarity to Pfam domain PF02845 CUE domain contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR002123 (Phospholipid/glycerol acyltransferase)
10	W05G11.2	W05G11.2	n/a	chrIII 58,191	contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal)
11	ula-1	C26E6.8	0.0000000000007	chrIII 4,919,320	The ula-1 gene encodes a component of the enzyme that activates NED-8, which in turn is a ubiquitin-like protein whose conjugating enzyme is UBC-12.
12	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
13	ZK686.2	ZK686.2	n/a	chrIII 7,764,804	ZK686.2 encodes a DEAD-box helicase; loss of ZK686.2 activity via RNAi indicates that ZK686.2 activity is required for positive regulation of growth rate and larval development.
14	sdz-6	C43D7.5	n/a	chrV 19,320,877	C. elegans SDZ-6 protein ; contains similarity to Dictyostelium discoideum AAC-rich mRNA clone AAC11 protein.; SW:P14196
15	F39B2.3	F39B2.3	n/a	chrI 14,788,812	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
16	tin-13	DY3.1	n/a	chrI 8,759,490	C. elegans TIN-13 protein; contains similarity to Pfam domain PF02953 Tim10/DDP family zinc finger contains similarity to Interpro domain IPR004217 (Zinc finger, Tim10/DDP-type)
17	D1081.8	D1081.8	n/a	chrI 8,493,557	contains similarity to Pfam domain PF00249 Myb-like DNA-binding domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR012287 (Homeodomain-related), IPR014778 (Myb, DNA-binding), IPR009057 (Homeodomain-like), IPR015495 (Myb transcription factor)
18	tag-203	K02F2.3	n/a	chrI 6,824,603	C. elegans TAG-203 protein; contains similarity to Pfam domain PF03178 CPSF A subunit region contains similarity to Interpro domains IPR004871 (Cleavage and polyadenylation specificity factor, A subunit, C-terminal), IPR011046 (WD40 repeat-like), IPR015943 (WD40/YVTN repeat-like)
19	ergo-1	R09A1.1	n/a	chrV 1,013,580	C. elegans ERGO-1 protein; contains similarity to Pfam domains PF02170 (PAZ domain) , PF02171 (Piwi domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
20	math-22	C46F9.1	n/a	chrII 1,905,746	C. elegans MATH-22 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
21	tre-3	W05E10.4	n/a	chrV 11,712,817	tre-3 encodes one of four putative trehalases in C. elegans of unknown function, as RNAi analysis has not produced an obvious phenotype; expressed throughout development.
22	dhs-21	R11D1.11	n/a	chrV 12,732,679	dhs-21 encodes a member of the short-chain dehydrogenases/reductases family (SDR) expressed in the intestine, hypodermis, uterus, and spermatheca.
23	sup-17	DY3.7	n/a	chrI 8,795,117	sup-17 encodes an ADAM protein, an integral membrane disintegrin and zinc-activated metalloproteinase, orthologous to Drosophila and mouse KUZBANIAN and the vertebrate ADAM10 proteins; SUP-17 is required maternally for embryonic development and plays a role in LIN-12/Notch-mediated cell signaling required for several cell fate decisions during vulval development; SUP-17 is also required for normal body morphology and male tail development; SUP-17 functions cell autonomously to facilitate LIN-12 signaling and requires the LIN-12 extracellular domain to do so.
24	eri-3	W09B6.3	n/a	chrII 1,125,668	C. elegans ERI-3 protein ;
25	ZK795.3	ZK795.3	n/a	chrIV 12,559,996	contains similarity to Pfam domain PF04427 Brix domain contains similarity to Interpro domain IPR007109 (Brix)
26	T02C12.3	T02C12.3	n/a	chrIII 4,023,867	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q16W48
27	Y40B1B.8	Y40B1B.8	n/a	chrI 13,431,748	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domain IPR001993 (Mitochondrial substrate carrier)
28	Y54G11A.2	Y54G11A.2	n/a	chrII 14,253,902	contains similarity to Pfam domain PF05670 Domain of unknown function (DUF814) contains similarity to Interpro domain IPR008532 (Protein of unknown function DUF814)
29	C38C10.2	C38C10.2	n/a	chrIII 9,388,833	C38C10.2 is orthologous to the human gene SOLUTE CARRIER FAMILY 17 (ANION/SUGAR TRANSPORTER), MEMBER 5 (SLC17A5; OMIM:604322), which when mutated leads to disease.
30	C24G6.3	C24G6.3	n/a	chrV 5,517,383	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
31	srx-29	K06B4.9	n/a	chrV 15,697,466	C. elegans SRX-29 protein ;
32	C05D11.9	C05D11.9	n/a	chrIII 6,429,174	C05D11.9 encodes an ortholog of Pop1, a protein subunit shared by the endoribonucleases RNase MRP and RNAse P; RNAse MRP cleaves mitochondrial RNA in mitochondrial DNA synthesis, nucleolar pre-rRNA in ribosome synthesis, and at least one mRNA (CLB2) involved in cell-cycle regulation; RNAse P cleaves tRNA precursors to produce their mature 5' end; C05D11.9 is evolutionarily ubiquitous among eukaryotes.
33	B0019.2	B0019.2	n/a	chrI 12,777,941	contains similarity to Pfam domains PF04435 (Domain of unknown function (DUF545)) , PF02178 (AT hook motif) contains similarity to Interpro domains IPR006570 (SPK), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR009057 (Homeodomain-like)
34	F58G6.3	F58G6.3	n/a	chrIV 9,653,835	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domains IPR007274 (Ctr copper transporter), IPR001463 (Sodium:alanine symporter)
35	F47G3.3	F47G3.3	n/a	chrX 2,377,319
36	C05D11.10	C05D11.10	n/a	chrIII 6,431,356	contains similarity to Interpro domain IPR016027 (Nucleic acid-binding, OB-fold-like)
37	srt-69	B0238.8	n/a	chrV 5,264,800	C. elegans SRT-69 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
38	C14A4.3	C14A4.3	n/a	chrII 10,586,058	contains similarity to Pfam domain PF03901 Alg9-like mannosyltransferase family contains similarity to Interpro domain IPR005599 (Alg9-like mannosyltransferase)
39	T13F2.2	T13F2.2	n/a	chrIV 9,797,072	contains similarity to Pfam domain PF02229 Transcriptional Coactivator p15 (PC4) contains similarity to Interpro domains IPR003173 (Transcriptional coactivator p15), IPR009044 (ssDNA-binding transcriptional regulator)
40	C23H3.5	C23H3.5	n/a	chrII 48,839
41	ttll-5	C55A6.2	n/a	chrV 11,510,749	ttll-5 encodes a putative tubulin polyglutamylase orthologous to human TTLL5; TTLL-5 is required for embryonic development and fertility; by orthology, TTLL-5 is expected to initiate glutamyl chains rather than elongating them, to prefer alpha-tubulin over beta-tubulin as a substrate, and to have non-tubulin substrates.
42	scpl-2	F45E12.1	n/a	chrII 7,312,591	scpl-2 encodes a putative serine/threonine phosphatase, orthologous to budding yeast Nem1p and human DULLARD; SCPL-2 is expressed in pharynx and intestine; SCPL-2 is distantly similar to FCP-1 and SCPL-1, -3, and -4; by orthology, SCPL-2 is expected to localize to the nuclear envelope, to regulate nuclear membrane biogenesis, and to dephosphorylate the phosphatidic acid phosphatase ortholog H37A05.1.
43	H41C03.3	H41C03.3	n/a	chrII 5,848,949	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
44	T12E12.2	T12E12.2	n/a	chrIV 5,546,641	contains similarity to Pfam domain PF00385 'chromo' (CHRromatin Organisation MOdifier) domain contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like)
45	R06F6.2	R06F6.2	n/a	chrII 10,790,634	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR016528 (Vacuolar protein sorting-associated protein 11), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000547 (Clathrin, heavy chain/VPS, 7-fold repeat), IPR016024 (Armadillo-type fold), IPR011044 (Quinoprotein amine dehydrogenase, beta chain-like)
46	cir-1	F55F8.4	n/a	chrI 5,654,871	C. elegans CIR-1 protein ; contains similarity to Homo sapiens Isoform 1 of CBF1-interacting corepressor; ENSEMBL:ENSP00000339723
47	inx-15	R12E2.9	n/a	chrI 4,160,065	C. elegans INX-15 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
48	F31E3.4	F31E3.4	n/a	chrIII 6,965,804	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR011046 (WD40 repeat-like), IPR006055 (Exonuclease), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
49	T12G3.5	T12G3.5	n/a	chrIV 12,031,705	contains similarity to Drosophila melanogaster Flybase gene name is mRpL51-PA;; FLYBASE:CG13098
50	smp-2	D1037.2	n/a	chrI 3,669,414	C. elegans SMP-2 protein; contains similarity to Pfam domain PF01403 Sema domain contains similarity to Interpro domains IPR001627 (Semaphorin/CD100 antigen), IPR003659 (Plexin/semaphorin/integrin), IPR016201 (Plexin-like fold), IPR015943 (WD40/YVTN repeat-like)