UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	PHO5	YBR093C	439	n/a	chrII 430,249	Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis secretory pathway derived cell surface glycoprotein induced by phosphate starvation and coordinately regulated by PHO4 and PHO2
2	ILS1	YBL076C	439	n/a	chrII 82,652	Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A
3	SPS4	YOR313C	439	n/a	chrXV 902,366	Protein whose expression is induced during sporulation not required for sporulation heterologous expression in E. coli induces the SOS response that senses DNA damage
4	NOP1	YDL014W	439	n/a	chrIV 427,855	Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA has similarity to mammalian fibrillarin
5	FAR1	YJL157C	439	n/a	chrX 125,082	Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating potential Cdc28p substrate
6	PHO3	YBR092C	439	n/a	chrII 428,399	Constitutively expressed acid phosphatase similar to Pho5p brought to the cell surface by transport vesicles hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake expression is repressed by thiamin
7	DBP2	YNL112W	439	n/a	chrXIV 414,960	Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
8	PHO84	YML123C	439	n/a	chrXIII 24,918	High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter regulated by Pho4p and Spt7p mutation confers resistance to arsenate exit from the ER during maturation requires Pho86p
9	CHA1	YCL064C	439	n/a	chrIII 16,339	Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine
10	RPL5	YPL131W	439	8e-150	chrXVI 303,567	Protein component of the large (60S) ribosomal subunit with similarity to E. coli L18 and rat L5 ribosomal proteins binds 5S rRNA and is required for 60S subunit assembly
11	NSR1	YGR159C	439	n/a	chrVII 807,034	Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis
12	URA1	YKL216W	439	n/a	chrXI 25,687	Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid
13	ERG3	YLR056W	439	n/a	chrXII 254,409	C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis mutants are viable, but cannot grow on non-fermentable carbon sources
14	ZRT1	YGL255W	439	n/a	chrVII 21,543	High-affinity zinc transporter of the plasma membrane, responsible for the majority of zinc uptake transcription is induced under low-zinc conditions by the Zap1p transcription factor
15	PHO11	YAR071W	439	n/a	chrI 226,161	One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway induced by phosphate starvation and coordinately regulated by PHO4 and PHO2
16	MAE1	YKL029C	439	n/a	chrXI 383,720	Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids
17	TAT1	YBR069C	439	n/a	chrII 377,503	Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter overexpression confers FK506 and FTY720 resistance
18	PHO12	YHR215W	439	n/a	chrVIII 552,800	One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway nearly identical to Pho11p upregulated by phosphate starvation
19	RPS20	YHL015W	439	n/a	chrVIII 75,594	Protein component of the small (40S) ribosomal subunit overproduction suppresses mutations affecting RNA polymerase III-dependent transcription has similarity to E. coli S10 and rat S20 ribosomal proteins
20	FET3	YMR058W	439	n/a	chrXIII 389,777	Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases
21	RHR2	YIL053W	439	n/a	chrIX 255,491	Constitutively expressed isoform of DL-glycerol-3-phosphatase involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress
22	LYS4	YDR234W	439	n/a	chrIV 932,169	Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway
23	YGR079W	YGR079W	439	n/a	chrVII 641,276	Putative protein of unknown function YGR079W is not an essential gene
24	AQR1	YNL065W	439	n/a	chrXIV 504,604	Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine involved in the excretion of excess amino acids
25	NOG1	YPL093W	439	n/a	chrXVI 371,949	Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis constituent of 66S pre-ribosomal particles member of the ODN family of nucleolar G-proteins
26	NAN1	YPL126W	439	n/a	chrXVI 311,555	U3 snoRNP protein, component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA required for the biogenesis of18S rRNA
27	HPT1	YDR399W	439	n/a	chrIV 1,270,400	Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
28	BFR2	YDR299W	439	n/a	chrIV 1,060,429	Essential protein that is a component of 90S preribosomes may be involved in rRNA processing multicopy suppressor of sensitivity to Brefeldin A expression is induced during lag phase and also by cold shock
29	RCL1	YOL010W	439	n/a	chrXV 308,489	Subunit of U3-containing 90S preribosome processome complex involved in 18S rRNA biogenesis and small ribosomal subunit assembly stimulates Bms1p GTPase and U3 binding activity similar to RNA cyclase-like proteins but no activity detected
30	ATO3	YDR384C	439	n/a	chrIV 1,241,617	Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell phosphorylated in mitochondria member of the TC 9.B.33 YaaH family of putative transporters
31	SFG1	YOR315W	439	n/a	chrXV 905,280	Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth may act together with Phd1p potential Cdc28p substrate
32	RRP12	YPL012W	439	n/a	chrXVI 531,566	Protein required for export of the ribosomal subunits associates with the RNA components of the pre-ribosomes has a role in nuclear import in association with Pse1p contains HEAT-repeats