UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	ARG4	YHR018C	409	n/a	chrVIII 140,706	Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway
2	LEU2	YCL018W	409	n/a	chrIII 91,871	Beta-isopropylmalate dehydrogenase (IMDH), catalyzes the third step in the leucine biosynthesis pathway
3	ARG3	YJL088W	409	n/a	chrX 269,307	Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine
4	HIS5	YIL116W	409	n/a	chrIX 143,506	Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis responsive to general control of amino acid biosynthesis mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts
5	CUP1-2	YHR055C	409	n/a	chrVIII 214,625	Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C
6	CUP1-1	YHR053C	409	n/a	chrVIII 212,627	Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C
7	ASP3-4	YLR160C	409	n/a	chrXII 486,745	Cell-wall L-asparaginase II involved in asparagine catabolism expression induced during nitrogen starvation ORF contains a short non-coding RNA that enhances expression of full-length gene reference strain S288C has four copies of ASP3
8	ASP3-3	YLR158C	409	n/a	chrXII 483,093	Cell-wall L-asparaginase II involved in asparagine catabolism expression induced during nitrogen starvation ORF contains a short non-coding RNA that enhances expression of full-length gene reference strain S288C has four copies of ASP3
9	ASP3-2	YLR157C	409	n/a	chrXII 473,513	Cell-wall L-asparaginase II involved in asparagine catabolism expression induced during nitrogen starvation ORF contains a short non-coding RNA that enhances expression of full-length gene reference strain S288C has four copies of ASP3
10	ASP3-1	YLR155C	409	n/a	chrXII 469,861	Cell-wall L-asparaginase II involved in asparagine catabolism expression induced during nitrogen starvation ORF contains a short non-coding RNA that enhances expression of full-length gene reference strain S288C has four copies of ASP3
11	INO4	YOL108C	409	n/a	chrXV 111,658	Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain
12	MET16	YPR167C	409	n/a	chrXVI 877,239	3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism
13	GAP1	YKR039W	409	n/a	chrXI 515,967	General amino acid permease Gap1p senses the presence of amino acid substrates to regulate localization to the plasma membrane when needed
14	YAP1	YML007W	409	n/a	chrXIII 254,824	Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus mediates resistance to cadmium
15	ARG1	YOL058W	409	n/a	chrXV 219,842	Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway potential Cdc28p substrate
16	AGP1	YCL025C	409	n/a	chrIII 76,968	Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)
17	CPS1	YJL172W	409	n/a	chrX 98,602	Vacuolar carboxypeptidase yscS expression is induced under low-nitrogen conditions
18	SNC2	YOR327C	409	n/a	chrXV 930,907	Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane member of the synaptobrevin/VAMP family of R-type v-SNARE proteins
19	SRY1	YKL218C	409	1e-164	chrXI 17,849	3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia required in the presence of hydroxyaspartate highly similar to mouse serine racemase (Srr) but has no serine racemase activity
20	MET1	YKR069W	409	n/a	chrXI 572,502	S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase required for sulfate assimilation and methionine biosynthesis
21	BAP2	YBR068C	409	n/a	chrII 374,775	High-affinity leucine permease, functions as a branched-chain amino acid permease involved in the uptake of leucine, isoleucine and valine contains 12 predicted transmembrane domains
22	FMO1	YHR176W	409	n/a	chrVIII 454,878	Flavin-containing monooxygenase, localized to the cytoplasmic face of the ER membrane catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins
23	LYS1	YIR034C	409	n/a	chrIX 420,175	Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway also has mRNA binding activity
24	MPT5	YGL178W	409	n/a	chrVII 168,961	Member of the Puf family of RNA-binding proteins binds to mRNAs encoding chromatin modifiers and spindle pole body components involved in longevity, maintenance of cell wall integrity, and sensitivity to and recovery from pheromone arrest
25	YAT2	YER024W	409	n/a	chrV 203,577	Carnitine acetyltransferase has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane
26	SER3	YER081W	409	n/a	chrV 323,390	3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis isozyme of Ser33p
27	SER33	YIL074C	409	n/a	chrIX 221,785	3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis isozyme of Ser3p
28	BNA3	YJL060W	409	n/a	chrX 324,053	Kynurenine aminotransferase, catalyzes formation of kynurenic acid from kynurenine potential Cdc28p substrate
29	PEX21	YGR239C	409	n/a	chrVII 969,620	Peroxin required for targeting of peroxisomal matrix proteins containing PTS2 interacts with Pex7p partially redundant with Pex18p
30	PDR10	YOR328W	409	n/a	chrXV 934,150	ATP-binding cassette (ABC) transporter, multidrug transporter involved in the pleiotropic drug resistance network regulated by Pdr1p and Pdr3p
31	MET13	YGL125W	409	n/a	chrVII 273,421	Major isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway
32	YGR125W	YGR125W	409	n/a	chrVII 743,880	Putative protein of unknown function deletion mutant has decreased rapamycin resistance but normal wormannin resistance green fluorescent protein (GFP)-fusion protein localizes to the vacuole
33	YPL088W	YPL088W	409	n/a	chrXVI 382,479	Putative aryl alcohol dehydrogenase transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
34	SNZ1	YMR096W	409	n/a	chrXIII 458,854	Protein involved in vitamin B6 biosynthesis member of a stationary phase-induced gene family coregulated with SNO1 interacts with Sno1p and with Yhr198p, perhaps as a multiprotein complex containing other Snz and Sno proteins
35	GFD1	YMR255W	409	n/a	chrXIII 778,284	Coiled-coiled protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation
36	ISA1	YLL027W	409	n/a	chrXII 87,779	Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency depletion reduces growth on nonfermentable carbon sources
37	YCT1	YLL055W	409	n/a	chrXII 30,906	High-affinity cysteine-specific transporter with similarity to the Dal5p family of transporters green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum YCT1 is not an essential gene
38	ORT1	YOR130C	409	n/a	chrXV 570,368	Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome
39	SKS1	YPL026C	409	n/a	chrXVI 501,429	Putative serine/threonine protein kinase involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway