UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	SUC2	YIL162W	619	n/a	chrIX 38,184	Invertase, sucrose hydrolyzing enzyme a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively
2	QCR6	YFR033C	619	n/a	chrVI 224,547	Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain highly acidic protein required for maturation of cytochrome c1
3	QCR7	YDR529C	619	n/a	chrIV 1,496,356	Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain oriented facing the mitochondrial matrix N-terminus appears to play a role in complex assembly
4	COX6	YHR051W	619	n/a	chrVIII 209,928	Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain expression is regulated by oxygen levels
5	ATP2	YJR121W	619	n/a	chrX 648,374	Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis phosphorylated
6	COX4	YGL187C	619	n/a	chrVII 149,937	Subunit IV of cytochrome c oxidase, the terminal member of the mitochondrial inner membrane electron transport chain precursor N-terminal 25 residues are cleaved during mitochondrial import phosphorylated spermidine enhances translation
7	COX8	YLR395C	619	n/a	chrXII 909,847	Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
8	ATP4	YPL078C	619	n/a	chrXVI 408,377	Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis contributes to the oligomerization of the complex phosphorylated
9	CYT1	YOR065W	619	n/a	chrXV 447,903	Cytochrome c1, component of the mitochondrial respiratory chain expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex
10	ATP1	YBL099W	619	n/a	chrII 37,871	Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis phosphorylated
11	COR1	YBL045C	619	n/a	chrII 134,829	Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain
12	QCR2	YPR191W	619	n/a	chrXVI 919,934	Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain phosphorylated transcription is regulated by Hap1p, Hap2p/Hap3p, and heme
13	RIP1	YEL024W	619	n/a	chrV 107,583	Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex transfers electrons from ubiquinol to cytochrome c1 during respiration
14	FUM1	YPL262W	619	n/a	chrXVI 48,069	Fumarase, converts fumaric acid to L-malic acid in the TCA cycle cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt phosphorylated in mitochondria
15	QCR8	YJL166W	619	n/a	chrX 106,576	Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain oriented facing the intermembrane space expression is regulated by Abf1p and Cpf1p
16	ATP5	YDR298C	619	n/a	chrIV 1,058,495	Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is an evolutionarily conserved enzyme complex required for ATP synthesis homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein) phosphorylated
17	COX7	YMR256C	619	n/a	chrXIII 779,036	Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
18	SNF3	YDL194W	619	n/a	chrIV 112,907	Plasma membrane low glucose sensor that regulates glucose transport contains 12 predicted transmembrane segments and a long C-terminal tail required for induction of hexose transporters also senses fructose and mannose similar to Rgt2p
19	YAK1	YJL141C	619	n/a	chrX 149,178	Serine-threonine protein kinase component of a glucose-sensing system that inhibits growth in response to glucose availability upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose
20	MDH1	YKL085W	619	n/a	chrXI 279,625	Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate involved in the tricarboxylic acid (TCA) cycle phosphorylated
21	PET9	YBL030C	619	n/a	chrII 163,519	Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP also imports heme and ATP phosphorylated required for viability in many lab strains that carry a sal1 mutation
22	KGD2	YDR148C	619	n/a	chrIV 754,370	Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle phosphorylated
23	QCR9	YGR183C	619	n/a	chrVII 859,269	Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain required for electron transfer at the ubiquinol oxidase site of the complex
24	MIR1	YJR077C	619	n/a	chrX 577,722	Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria functionally redundant with Pic2p but more abundant than Pic2p under normal conditions phosphorylated
25	ATP7	YKL016C	619	2e-94	chrXI 407,727	Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
26	GUT1	YHL032C	619	n/a	chrVIII 37,443	Glycerol kinase, converts glycerol to glycerol-3-phosphate glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p
27	NDI1	YML120C	619	n/a	chrXIII 29,036	NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I phosphorylated homolog of human AMID
28	COX13	YGL191W	619	n/a	chrVII 145,002	Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain not essential for cytochrome c oxidase activity but may modulate activity in response to ATP
29	SUR1	YPL057C	619	n/a	chrXVI 452,483	Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p function in sphingolipid biosynthesis is overlapping with that of Csh1p
30	SDH3	YKL141W	619	n/a	chrXI 179,965	Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain
31	SIP2	YGL208W	619	n/a	chrVII 97,961	One of three beta subunits of the Snf1 serine/threonine protein kinase complex involved in the response to glucose starvation null mutants exhibit accelerated aging N-myristoylprotein localized to the cytoplasm and the plasma membrane
32	CBP4	YGR174C	619	n/a	chrVII 846,149	Mitochondrial protein required for assembly of cytochrome bc1 complex interacts with the Cbp3p-Cbp6p complex and newly synthesized cytochrome b (Cobp) to promote assembly of Cobp into the cytochrome bc1 complex
33	SDH4	YDR178W	619	n/a	chrIV 818,222	Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain
34	ATP3	YBR039W	619	n/a	chrII 316,042	Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
35	MAL31	YBR298C	619	n/a	chrII 803,553	Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter) encoded in the MAL3 complex locus member of the 12 transmembrane domain superfamily of sugar transporters functional in genomic reference strain S288C
36	MAL33	YBR297W	619	n/a	chrII 801,226	MAL-activator protein, part of complex locus MAL3 nonfunctional in genomic reference strain S288C
37	REG2	YBR050C	619	n/a	chrII 337,691	Regulatory subunit of the Glc7p type-1 protein phosphatase involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease
38	MEF2	YJL102W	619	n/a	chrX 232,530	Mitochondrial elongation factor involved in translational elongation
39	SPG5	YMR191W	619	n/a	chrXIII 646,216	Protein required for survival at high temperature during stationary phase not required for growth on nonfermentable carbon sources
40	ECL1	YGR146C	619	n/a	chrVII 784,540	Protein of unknown function, affects chronological lifespan induced by iron homeostasis transcription factor Aft2p multicopy suppressor of temperature sensitive hsf1 mutant induced by treatment with 8-methoxypsoralen and UVA irradiation
41	ESBP6	YNL125C	619	n/a	chrXIV 391,156	Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane
42	APJ1	YNL077W	619	n/a	chrXIV 482,184	Putative chaperone of the HSP40 (DNAJ) family overexpression interferes with propagation of the [Psi+] prion the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
43	SDH1	YKL148C	619	n/a	chrXI 170,168	Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain
44	COX12	YLR038C	619	n/a	chrXII 225,046	Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain required for assembly of cytochrome c oxidase but not required for activity after assembly phosphorylated
45	ODC1	YPL134C	619	n/a	chrXVI 299,037	Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for lysine and glutamate biosynthesis and lysine catabolism suppresses, in multicopy, an fmc1 null mutation
46	VHS1	YDR247W	619	n/a	chrIV 956,705	Cytoplasmic serine/threonine protein kinase identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression homolog of Sks1p
47	GIS1	YDR096W	619	n/a	chrIV 638,481	JmjC domain-containing histone demethylase and transcription factor involved in expression of genes during nutrient limitation negatively regulates DPP1 and PHR1 activity is modulated by limited proteasome-mediated proteolysis has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain
48	YMR031C	YMR031C	619	n/a	chrXIII 333,477	Component of the eisosome that is required for proper eisosome assembly similarity to Ykl050cp and Uso1p the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies
49	YLR177W	YLR177W	619	n/a	chrXII 511,997	Putative protein of unknown function phosphorylated by Dbf2p-Mob1p in vitro some strains contain microsatellite polymophisms at this locus YLR177W is not an essential gene
50	ATP17	YDR377W	619	n/a	chrIV 1,228,763	Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis