Gene interactions and pathways from curated databases and text-mining

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RHO — STK16

Text-mined interactions from Literome

Hamaguchi et al., Biochem Biophys Res Commun 2000 : Phosphorylation of CPI-17 by protein kinase N ( PKN ), a fatty acid- and Rho activated serine/threonine kinase , and its effect on smooth muscle myosin phosphatase activity were investigated
Löhn et al., Eur J Pharmacol 2005 : Vasoconstrictor factors, like urotensin, angiotensin and catecholamines, activate Rho dependent serine-threonine kinase ( Rho-kinase ) and inhibition of this pathway represents a novel therapy for cardiovascular diseases with hypertensive syndrome
Rupérez et al., Kidney Int Suppl 2005 (Kidney Diseases) : AngII via AngII type 1 receptors activates several intracellular signaling systems, including the small guanosine triphosphatase Rho and its downstream effector Rho dependent serine-threonine kinase ( Rho-kinase )
Gavard et al., J Biol Chem 2008 : Instead, we found that protein kinase C-related kinase, a Rho dependent serine/threonine kinase , is activated in endothelial cells upon thrombin stimulation and that its expression is required for endothelial permeability and the remodeling of cell-extracellular matrix and cell-cell adhesions