Gene interactions and pathways from curated databases and text-mining

◀ Back to PTPN6

CSF2RB — PTPN6

Pathways - manually collected, often from reviews:

  • BioCarta il 3 signaling pathway: SHP-1 (PTPN6) → IL-3/IL-3R-alpha/IL-3R-beta complex (IL3RA-IL3-CSF2RB) (modification, inhibits)
  • KEGG Jak-STAT signaling pathway: PTPN6 → CNTFR/CRLF2/CSF2RA/CSF2RB/CSF3R/EPOR/GHR/IFNAR1/IFNAR2/IFNGR1/IFNGR2/IFNLR1/IL10RA/IL10RB/IL11RA/IL12RB1/IL12RB2/IL13RA1/IL13RA2/IL15RA/IL20RA/IL20RB/IL21R/IL22RA1/IL22RA2/IL23R/IL2RA/IL2RB/IL2RG/IL3RA/IL4R/IL5RA/IL6R/IL6ST/IL7R/IL9R/LEPR/LIFR/MPL/OSMR/PRLR (protein-protein, inhibition)
  • Reactome Reaction: CSF2RB → PTPN6 (indirect_complex) Bone et al., J Biol Chem 1997
  • Reactome Reaction: CSF2RB → PTPN6 (reaction) Bone et al., J Biol Chem 1997

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *