Negulescu et al., Kidney Int 2002
:
The effects of TGF-beta1 on mesangial cell apoptosis, p53 phosphorylation, Bax and Bcl-2 levels, caspase 9 activity, and cleavage of PARP were examined
Yang et al., Int J Biochem Cell Biol 2004
:
In addition, we observed that both TGF-beta1 induced apoptosis and PARP degradation in AML-12 cells can be completely blocked by inhibiting the protein synthesis with cycloheximide
Filyak et al., Cell Biol Int 2007
(Adenocarcinoma) :
Western-blot analysis and immunocytochemistry were used to show that doxorubicin induced PARP degradation in A549 cells, and TGFbeta-1 enhanced that action of the drug