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IRF1 — NOS3
Text-mined interactions from Literome
Lee et al., Biochim Biophys Acta 2008
(Neoplasms...) :
In addition,
IRF-1 directly inhibited the tube formation of endothelial cells on Matrigel and
reduced the expression of p-Akt, and
p-eNOS , which play a significant role in angiogenesis when stimulated by VEGF ... In addition,
IRF-1 directly inhibited the tube formation of endothelial cells on Matrigel and
reduced the expression of p-Akt, and
p-eNOS , which play a significant role in angiogenesis when stimulated by VEGF
Martin et al., J Exp Med 1994
:
Role of
interferon regulatory factor 1 in induction of
nitric oxide synthase
Vilcek et al., Int Arch Allergy Immunol 1994
(Bacterial Infections) :
Other studies have shown that the transcription factor
IRF-1 is
essential for the IFN-gamma mediated activation of the gene for the inducible
nitric oxide synthase
Hecker et al., Br J Pharmacol 1996
:
Inhibition by antioxidants of
nitric oxide synthase expression in murine macrophages :
role of nuclear factor kappa B and
interferon regulatory factor 1