Gene interactions and pathways from curated databases and text-mining

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AKT1 — LTB

Text-mined interactions from Literome

Klein et al., Cell Signal 2001 (MAP Kinase Signaling System) : LPS, fMLP, and LTB ( 4 ) stimulated similar levels of ERK and Akt activation
Tong et al., Biochem Biophys Res Commun 2005 (Pancreatic Neoplasms) : Phosphorylation of Akt was also induced by LTB4 and this effect was blocked by the PI-3 kinase inhibitor wortmannin, which also partially blocked LTB4 stimulated cell proliferation
Watanabe et al., J Allergy Clin Immunol 2009 : LTB4 also induced phosphorylation of both p42/p44 mitogen activated protein kinase ( MAPK ) and downstream PI3 kinase effector, Akt1