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BCL10 — TCF4
Text-mined interactions from Literome
Sevilla et al., Mol Cell Biol 1999
:
The bcl-x promoter contains potential Ets binding sites, and we show that the
transcription factor , Ets2, first identified by its sequence identity to v-ets of the E26 retrovirus, can
transactivate the
bcl-x promoter
Tamatani et al., J Biol Chem 1999
:
To examine the possible
involvement of a
transcription factor , NFkappaB, in the regulation of Bcl-2 and
Bcl-x expression in TNF treated neurons, an adenoviral vector capable of expressing a mutated form of IkappaB was used to infect neurons prior to TNF treatment
Glasgow et al., Neurochem Res 2000
(Neurodegenerative Diseases) :
Key in these cascades is the
activation of the caspase and
Bcl-family of proteins by the NF-kappaB
transcription factor
Greten et al., Gastroenterology 2002
(Carcinoma, Ductal, Breast...) :
Inhibition of either
transcription factor alone
leads to
Bcl-x ( L ) down-regulation in transient transfection assays
Xie et al., Crit Rev Immunol 2006
:
However,
TCF-1 and ROR gamma t by themselves are not
sufficient to stimulate
Bcl-xL expression
Gyamfi et al., J Pharmacol Exp Ther 2008
(Inflammation...) :
Furthermore, signal transducer and activator of
transcription factor ( STAT ) 3 and associated
Bcl-xL induction was observed in ethanol fed wild-type mice but not in ethanol fed hepatocyte RXRalpha-deficient mice
Lapham et al., Gene 2009
(Colorectal Neoplasms) :
The
Bcl-w promoter is
activated by
beta-catenin/TCF4 in human colorectal carcinoma cells ... The activity of the
Bcl-w promoter was
increased or decreased, respectively, by overexpression of beta-catenin or dominant negative
TCF4
Chen et al., J Bone Miner Res 2010
:
Application of GATA-3 small interfering siRNA into osteoblasts decreased the levels of this
transcription factor and simultaneously
inhibited Bcl-X ( L ) mRNA synthesis