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MMP15 — TLR4

Text-mined interactions from Literome

Voelcker et al., Exp Dermatol 2008 (Disease Progression...) : Together, our results suggest that sHA in melanoma might promote tumor invasiveness by inducing MMP- and cytokine-expression, in part in a TLR4 dependent manner, providing new insights into the relationship between cancer and innate immunity
West et al., J Cell Biol 2008 : Surprisingly, MMP inhibitors block TLR signaling induced podosome disassembly, although stimulated endocytosis is unaffected, which demonstrates that the two phenomena are not obligatorily coupled
Ta et al., Atherosclerosis 2010 : Taken together, this study showed for the first time that the inhibition of DPP-4/CD26 by alogliptin suppressed TLR4 mediated ERK activation and ERK dependent MMP expression by U937 cells, suggesting that DPP-4/CD26 may play an important role in macrophage mediated inflammation response and tissue remodeling
Samuvel et al., Endocrinology 2011 (Obesity) : Furthermore, although it has been shown that Toll-like receptor 4 (TLR4), a receptor mediating innate immune response, plays an important role in the obesity associated inflammation and insulin resistance, the effect of TLR4 activation in coculture of adipocytes and monocytes on MMP production has not been investigated