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DEFB4B — TLR4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: DEFB4B, DEFB4A — TLR4 (in vivo) Biragyn et al., Science 2002*
• IRef Hprd Interaction: DEFB4B, DEFB4A — TLR4 (in vitro) Biragyn et al., Science 2002*

Text-mined interactions from Literome

Biragyn et al., Science 2002 (Neoplasms) : Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2
Vora et al., J Immunol 2004 : Beta-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells
MacRedmond et al., Respir Res 2005 : Respiratory epithelial cells require Toll-like receptor 4 for induction of human beta-defensin 2 by lipopolysaccharide
Frei et al., PloS one 2010 : We found that co-expression of MHC class II molecules and TLR2 or TLR4 in human embryonic kidney (HEK) cells 293 leads to enhanced production of the anti-microbial peptide human-beta-defensin (hBD) 2 after treatment with TLR2 stimulus bacterial lipoprotein (BLP) or TLR4 ligand lipopolysaccharide (LPS), respectively