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CXCL17 — TLR4
Text-mined interactions from Literome
Méndez-Samperio et al., Arch Med Res 2008
:
Moreover, it is important to note that the levels of
CXCL8 secretion and mRNA were markedly ( 94 % )
reduced by functional blocking of both TLR2 and
TLR4
Wang et al., Blood 2008
:
We and others have reported that
Toll-like receptor ( TLR ) proteins are present on human neutrophils and that granulocyte-macrophage colony stimulating factor ( GM-CSF ) treatment
enhances IL-8 (
CXCL8 ) secretion in response to stimulation with TLR ligands
Hoth et al., Shock 2009
(Contusions...) :
Increased expression of IL-6 and
chemokine ( C-X-C motif ) ligand 1 in the bronchoalveolar lavage and serum was also
dependent on
TLR-4 activation
Lee et al., Cell Microbiol 2009
:
In addition,
TLR2 , Dectin-1 and, to an extent, TLR4 are
essential for the MU-mediated expression of
CXCL8 , CCL2 and LL-37 in keratinocytes
Gasparoto et al., Med Mycol 2010
(Candidiasis...) :
Our results show that the absence of functional
TLR4 resulted in lower chemotaxis of neutrophils to the site of infection, lower levels of TNF-a,
CXCL1 and nitric oxide, and dissemination and persistence of the pathogen in lymph nodes and spleen
Sahin et al., Hepatology 2013
(Carbon Tetrachloride Poisoning...) :
Proapoptotic effects of the chemokine,
CXCL 10 are
mediated by the noncognate receptor
TLR4 in hepatocytes
Sharma et al., J Leukoc Biol 2013
:
Our findings reveal a previously unrecognized role for S1P in regulating
TLR induced
CXCL8 secretion from human T cells