Gene interactions and pathways from curated databases and text-mining

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CXCL17 — TLR4

Text-mined interactions from Literome

Méndez-Samperio et al., Arch Med Res 2008 : Moreover, it is important to note that the levels of CXCL8 secretion and mRNA were markedly ( 94 % ) reduced by functional blocking of both TLR2 and TLR4
Wang et al., Blood 2008 : We and others have reported that Toll-like receptor ( TLR ) proteins are present on human neutrophils and that granulocyte-macrophage colony stimulating factor ( GM-CSF ) treatment enhances IL-8 ( CXCL8 ) secretion in response to stimulation with TLR ligands
Hoth et al., Shock 2009 (Contusions...) : Increased expression of IL-6 and chemokine ( C-X-C motif ) ligand 1 in the bronchoalveolar lavage and serum was also dependent on TLR-4 activation
Lee et al., Cell Microbiol 2009 : In addition, TLR2 , Dectin-1 and, to an extent, TLR4 are essential for the MU-mediated expression of CXCL8 , CCL2 and LL-37 in keratinocytes
Gasparoto et al., Med Mycol 2010 (Candidiasis...) : Our results show that the absence of functional TLR4 resulted in lower chemotaxis of neutrophils to the site of infection, lower levels of TNF-a, CXCL1 and nitric oxide, and dissemination and persistence of the pathogen in lymph nodes and spleen
Sahin et al., Hepatology 2013 (Carbon Tetrachloride Poisoning...) : Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes
Sharma et al., J Leukoc Biol 2013 : Our findings reveal a previously unrecognized role for S1P in regulating TLR induced CXCL8 secretion from human T cells