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CDH18 — FGFR1
Text-mined interactions from Literome
Erez et al., Exp Cell Res 2004
:
Interestingly, addition of basic fibroblast growth factor to confluent, peptide treated, endothelial cell cultures, completely blocks apoptosis and the inhibitory peptide reduce the phosphorylation of the FGF receptor target protein FRS2, suggesting that the peptide exerts its effect by inhibiting
cadherin mediated activation of
fibroblast growth factor receptor signaling
Rachagani et al., Carcinogenesis 2012
(Neoplasm Invasiveness...) :
The downregulation of
FGFR1 in turn
led to downregulation of pAkt, pERK1/2, pNF-?B, pIkBa, uPA, MMP-9, vimentin, N-cadherin, Twist, Slug and Zeb1 and upregulation of
E-cadherin , Occludin, Cytokeratin-18 and Caspase-9 in MUC4 knockdown BXPC3 and Capan1 cells compared with scramble vector transfected cells