Gene interactions and pathways from curated databases and text-mining

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APC — CDH18

Text-mined interactions from Literome

Tselepis et al., Digestion 2000 (Adenocarcinoma...) : Progression along this pathway is characterized by changes in intercellular adhesion, in particular, loss of adenomatous polyposis coli , reduced cadherin expression and increased catenin phosphorylation resulting in its nuclear translocation
Malarkannan et al., J Immunol 2012 : This includes actin polymerization, tubulin multimerization, microtubule organizing center formation, calcium/calmodulin signaling, Pak/Raf/Mek1/2 mediated Erk1/2 activation, formation of maestrosome, E-cadherin , and CD44 mediated signaling and glycogen synthase kinase-3/adenomatous polyposis coli mediated ß-catenin activation