Xie et al., Diabetes 2008
:
We conclude that AMPK activation increases UCP-2 , resulting in the inhibition of both O ( 2 ). ( - ) and prostacyclin synthase nitration in diabetes
Shang et al., Hepatology 2009
(Acute Lung Injury...) :
Importantly, we show that inhibition of UCP2 activity by its pharmacological inhibitor genipin prevents LPS/GalN induced ATP reduction, AMPK activation, and apoptosis
Xu et al., Arterioscler Thromb Vasc Biol 2011
(Ischemia) :
We conclude that AMPK dependent UCP2 expression in ECs promotes angiogenesis in vivo