Gene interactions and pathways from curated databases and text-mining

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CDH2 — HRAS

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: CDH2 → HRAS (increases, HRAS Translocation, CDH2 Activity) Wu et al., Exp Cell Res 2008*
    Evidence: Infecting HUVECs with a dominant negative H-Ras mutant (Ras(S17N)) interferes bFGF-mediated cadherin downregulation, and the result suggests that bFGF attenuates surface cadherin expression on HUVECs via FGFR1 and intracellular Ras-JNK signaling.