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SOCS1 — VAV1

Pathways - manually collected, often from reviews:

• NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit): GRB2 (GRB2) → GRB2/SOCS1/VAV1 complex (GRB2-SOCS1-VAV1) (modification, collaborate)
  Alai et al., J Biol Chem 1992
  Evidence: assay
• NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit): SOCS1 (SOCS1) → GRB2/SOCS1/VAV1 complex (GRB2-SOCS1-VAV1) (modification, collaborate)
  Alai et al., J Biol Chem 1992
  Evidence: assay
• NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit): SOCS1 (SOCS1) → VAV1 (VAV1) (modification, collaborate) Alai et al., J Biol Chem 1992
  Evidence: assay
• NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit): GRB2/SOCS1/VAV1 complex (GRB2-SOCS1-VAV1) → VAV1 (VAV1) (modification, collaborate) Alai et al., J Biol Chem 1992
  Evidence: assay
• NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit): None → GRB2/SOCS1/VAV1 complex (GRB2-SOCS1-VAV1) (modification, collaborate)
  
• NCI Pathway Database Signaling events mediated by Stem cell factor receptor (c-Kit): GRB2/SOCS1/VAV1 complex (GRB2-SOCS1-VAV1) → None (modification, activates)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: SOCS1 — VAV1 De Sepulveda et al., EMBO J 1999
• IRef Bind_translation Interaction: SOCS1 — VAV1 (two hybrid) De Sepulveda et al., EMBO J 1999
• IRef Bind_translation Interaction: SOCS1 — VAV1 (coimmunoprecipitation) De Sepulveda et al., EMBO J 1999
• IRef Biogrid Interaction: SOCS1 — VAV1 (physical association, affinity chromatography technology) De Sepulveda et al., J Biol Chem 2000*
• IRef Biogrid Interaction: SOCS1 — VAV1 (physical association, affinity chromatography technology) De Sepulveda et al., EMBO J 1999
• IRef Hprd Interaction: SOCS1 — VAV1 (two hybrid) De Sepulveda et al., EMBO J 1999
• IRef Hprd Interaction: SOCS1 — VAV1 (in vivo) De Sepulveda et al., EMBO J 1999
• IRef Hprd Interaction: SOCS1 — VAV1 (in vitro) De Sepulveda et al., EMBO J 1999
• IRef Ophid Interaction: SOCS1 — VAV1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: SOCS1 — VAV1 (aggregation, confirmational text mining) De Sepulveda et al., EMBO J 1999