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PAK4 — VAV1

Text-mined interactions from Literome

Fernandez-Zapico et al., Cancer Cell 2005 (Adenocarcinoma...) : Mechanistically, the effects of Vav1 require its GEF activity and the activation of Rac1, PAK1 , and NF-kappaB and involve cyclin D1 upregulation
Wilsbacher et al., Cell communication and signaling : CCS 2006 : In addition, activation of ERK downstream of Vav1 is dependent on autocrine EGF receptor stimulation while active Vav1 can stimulate Rac1 and PAK activation independent of ligand binding to the EGF receptor