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IL22 — VAV1
Text-mined interactions from Literome
Hanazono et al., Acta Haematol 1996
:
Here we report that granulocyte/macrophage-colony- stimulating factor ( GM-CSF ),
interleukin-3 , and erythropoietin (Epo)
induce rapid and transient tyrosine phosphorylation of
Vav and that Vav is constitutively associated with the SH3 domain of Grb2/Ash in a human leukemia cell line UT-7
Fischer et al., Curr Biol 1998
:
Vav is a crucial regulator of TCR mediated Ca2+ flux, cytoskeletal reorganization and TCR clustering, and these are
required for T-cell maturation,
interleukin-2 production and cell cycle progression