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AKT2 — VAV1
Text-mined interactions from Literome
Hebeis et al., Blood 2005
:
Likewise, activation of
Akt ( a PI3K [ phosphatidylinositol 3-kinase ] target ) and phosphorylation of IkappaBalpha in response to CD180 or LPS
required Vav1 and Vav2, while Vav1 deficiency led to defective responses to CD180
Miranti et al., Curr Biol 1998
:
Additionally, Syk and
Vav1 cooperatively
induced activation of Jun N-terminal kinase (JNK), extracellular-signal regulated kinase 2 ( ERK2 ) and the kinase
Akt , and phosphorylation of the oncoprotein Cbl in fibrinogen-adherent cells