◀ Back to IL15

IL15 — VDR

Text-mined interactions from Literome

Krutzik et al., J Immunol 2008 : In this study, we found that TLR2/1 induced IL-15 was required for induction of CYP27b1, the VDR and the downstream antimicrobial peptide cathelicidin ... Although both IL-15 and IL-4 triggered macrophage differentiation, only IL-15 was sufficient by itself to induce CYP27b1 and subsequent bioconversion of 25-hydroxyvitamin D3 ( 25D3 ) into bioactive 1,25D3, leading to VDR activation and induction of cathelicidin
Bruce et al., J Immunol 2011 (Disease Models, Animal...) : Low proliferation of DN TCRaß ( + ) T cells was a result of the very low expression of the IL-15R in this population of cells in the absence of the VDR
Kato et al., J Clin Invest 1993 : Effects of interleukin-1 on syntheses of alkaline phosphatase, type X collagen, and 1,25-dihydroxyvitamin D3 receptor , and matrix calcification in rabbit chondrocyte cultures