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PLD6 — STSP1

Text-mined interactions from Literome

Jung et al., Carcinogenesis 1999 : In contrast, Stsp did not acutely activate PLD and inhibited acute TPA induced activation of PLD ... However, the less efficacious ( and more gradual ) sustained activation of PLD by Stsp may allow a patterned differentiation more like that observed in skin
Mockel et al., Endocrinology 1994 : The effects of phorbol dibutyrate ( PDBu ) on phosphatidylbutanol ( PtdBut ) generation in [ 3H ] palmitate- or [ 3H ] myristate prelabeled dog thyroid slices were measured to assess the activity of phospholipase-D ( PLD ) in the presence or absence of the two inhibitors of protein kinase-C ( PKC ), staurosporine (STSP) and calphostin-C
Lejeune et al., J Clin Endocrinol Metab 1996 : In cultured dog thyrocytes, phorbol esters, and STSP induced DNA synthesis and dedifferentiation, whereas thapsigargin inhibited TSH induced growth and killed phorbol esters stimulated cells, suggesting a positive role of PLD stimulation towards dedifferentiated growth and of simultaneously raised [Ca2+ ) i and stimulated protein kinase C-PLD towards growth arrest and cellular death