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MAPK8 — PTTG1

Text-mined interactions from Literome

Chamaon et al., Biochem Biophys Res Commun 2005 (Astrocytoma) : This suggest, that PI3K and MAPK signalling is involved in PTTG regulation not only in malignant astrocytomas but also in non-tumorous cells
Vlotides et al., Mol Endocrinol 2006 (Pituitary Neoplasms) : Phosphatidylinositol 3 kinase, protein kinase C, and MAPK , but not c-Jun N-terminal kinase and Janus activating kinase signaling regulated EGF induced Pttg1 , as well as proliferating cell nuclear antigen mRNA expression and entry into S-phase
Chesnokova et al., Mol Endocrinol 2012 (Chromosomal Instability...) : FOXL2 directly stimulates the Clu gene promoter, and we show that PTTG triggers ataxia telangiectasia mutated kinase/IGF-I/p38MAPK DNA damage/chromosomal instability signaling, which in turn also induces Clu expression
Chen et al., PloS one 2013 : The protein kinase C ( PKC ) inhibitor and the MAPK/ERK kinase (MEK) inhibitor significantly blocked the potentiation of PMA mediated KLF6 induction and the down-regulation of PTTG1 , indicating that PTTG1 is suppressed via the activation of PKC/ERK/KLF6 pathway