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APOB — COA6

Text-mined interactions from Literome

Al Rayyes et al., Eur J Pharmacol 1999 : We also investigated the effect of indomethacin on LDL binding in the presence of the 3-hydroxy-3-methylglutaryl CoA ( HMG CoA) reductase inhibitor, fluvastatin
Gaertner et al., Z Gastroenterol 1978 : After two days in culture no supressant effect of LDL on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity ( HMG-CoA ) was detected
Shakespeare et al., Atherosclerosis 1979 : The activity of the enzyme hydroxymethylglutaryl-CoA reductase and its repression by LDL has also been investigated in these fibroblast strains and in senescent cells of the foetal lung cell strain MRC-5
Ranganathan et al., Biochem J 1986 : VLDL, but not LDL , activated acyl-CoA : cholesterol acyltransferase ( ACAT ) and increased cholesterol accumulation in these cells
Drevon et al., J Lipid Res 1981 : In rat cells, human LDL caused only very small increases in cell cholesterol content and acylCoA : cholesterol acyltransferase ( ACAT ) activity and caused only small decreases in beta-hydroxy-beta-methylglutaryl CoA ( HMG CoA) reductase activity ; in human cells, however, human LDL induced very large changes in all three of these parameters, as expected