Tepper et al., Prostate 2007
(Neoplasms, Hormone-Dependent...) :
GCP markedly suppressed mTOR-p70S6K signaling while Akt and p53 were only modestly modulated
Shrivastava et al., Mol Cancer Ther 2011
(Breast Neoplasms) :
We showed that CBD induces endoplasmic reticulum stress and, subsequently, inhibits AKT and mTOR signaling as shown by decreased levels of phosphorylated mTOR and 4EBP1, and cyclin D1