We have a suspicion that you are an automated web bot software, not a real user.
To keep our site fast for other users, we have slowed down this page.
The slowdown will gradually disappear.
If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu.
Also note that all data for hgGeneGraph can be obtained through our public MySQL server and
all our software source code is available and can be installed locally onto your own computer.
If you are unsure how to use these resources, do not hesitate to contact us.
Weimbs et al., Cell cycle (Georgetown, Tex.) 2006
(Polycystic Kidney Diseases) :
In ADPKD, defects in PC1 would lead to constitutive activation of mTOR , and the affected cells would be engaged in a permanent state of futile repair leading to the formation and growth of renal cysts
Aguiari et al., Am J Nephrol 2013
(Polycystic Kidney, Autosomal Dominant) :
Furthermore, PC1 loss of function also induces activation of mTOR and EGFR signaling