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MTOR — SRL
Text-mined interactions from Literome
Grinyó et al., Am J Transplant 2006
:
MMF, a reversible inhibitor of inosin monophosphate dehydrogenase ( IMPDH ) acts as an antiproliferative drug ; and
SRL , an
mTOR ( mammalian target of rapamycin )
inhibitor , inhibits cell proliferation driven by growth factors
Masri et al., Transplant Proc 2007
:
SRL inhibits
mammalian target of rapamycin (TOR) , which is an enzyme critical to the immune function
Reis et al., Transplant Proc 2009
(Hypertension) :
Thus, the hypertensive effects of CsA, a calcineurin inhibitor, and of
SRL , an
mTOR inhibitor , are associated with impairment of distinct cardiovascular pathways
Kasap et al., Pediatr Transplant 2011
(Hyperlipidemias...) :
SRL , an
mTOR inhibitor that inhibits cell cycle progression, represents an important alternative to CNIs, which are still the cornerstones of pediatric solid organ tx