◀ Back to MTOR

MTOR — YWHAQ

Pathways - manually collected, often from reviews:

• NCI Pathway Database LKB1 signaling events: 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) → mTORC1 complex complex (MTOR-MLST8-RPTOR-AKT1S1) (modification, collaborate)
  Shaw et al., Cancer Cell 2004, Gwinn et al., Mol Cell 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database LKB1 signaling events: 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) → mTORC1 complex/14-3-3 family complex (MTOR-MLST8-RPTOR-AKT1S1-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (modification, collaborate)
  Shaw et al., Cancer Cell 2004, Gwinn et al., Mol Cell 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database LKB1 signaling events: mTORC1 complex complex (MTOR-MLST8-RPTOR-AKT1S1) → mTORC1 complex/14-3-3 family complex (MTOR-MLST8-RPTOR-AKT1S1-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (modification, collaborate)
  Shaw et al., Cancer Cell 2004, Gwinn et al., Mol Cell 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database mTOR signaling pathway: 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) → mTORC1/PRAS40/DEPTOR complex (MTOR-MLST8-AKT1S1-DEPTOR-RPTOR) (modification, collaborate)
  Gwinn et al., Mol Cell 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database mTOR signaling pathway: 14-3-3 family (YWHAH/YWHAZ/YWHAQ/SFN/YWHAE/YWHAG/YWHAB) → mTORC1/PRAS40/DEPTOR/14-3-3 family complex (MTOR-MLST8-AKT1S1-DEPTOR-RPTOR-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (modification, collaborate)
  Gwinn et al., Mol Cell 2008
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database mTOR signaling pathway: mTORC1/PRAS40/DEPTOR complex (MTOR-MLST8-AKT1S1-DEPTOR-RPTOR) → mTORC1/PRAS40/DEPTOR/14-3-3 family complex (MTOR-MLST8-AKT1S1-DEPTOR-RPTOR-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB) (modification, collaborate)
  Gwinn et al., Mol Cell 2008
  Evidence: mutant phenotype, assay, physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: YWHAQ — MTOR Mori et al., FEBS Lett 2000*
• IRef Bind_translation Interaction: YWHAQ — MTOR (unspecified method) Mori et al., FEBS Lett 2000*
• IRef Biogrid Interaction: YWHAQ — MTOR (physical association, affinity chromatography technology) Meek et al., J Biol Chem 2004
• IRef Hprd Interaction: YWHAQ — MTOR (in vitro) Mori et al., FEBS Lett 2000*
• IRef Hprd Interaction: YWHAQ — MTOR (in vivo) Mori et al., FEBS Lett 2000*
• IRef Innatedb Interaction: YWHAQ — MTOR (unknown, -) Mori et al., FEBS Lett 2000*
• IRef Mppi Interaction: YWHAQ — MTOR (coimmunoprecipitation) Mori et al., FEBS Lett 2000*
• IRef Mppi Interaction: YWHAQ — MTOR (far western blotting) Mori et al., FEBS Lett 2000*
• IRef Ophid Interaction: YWHAQ — MTOR (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: YWHAQ — MTOR (aggregation, confirmational text mining) Mori et al., FEBS Lett 2000*