Gene interactions and pathways from curated databases and text-mining

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FKBP4 — MTOR

Text-mined interactions from Literome

Pieretti-Vanmarcke et al., Proc Natl Acad Sci U S A 2006 (Ovarian Neoplasms) : Because MIS releases FK506 binding protein ( FKBP12 ), which activates the mammalian target of rapamycin (mTOR) downstream of Akt, rhMIS and rapamycin combinations were tested
Wang et al., J Biol Chem 2008 : Furthermore, FKBP38 did not inhibit mTORC1 signaling
März et al., Mol Cell Biol 2013 : When the rapamycin dosage is limiting, mTOR inhibition of S6K phosphorylation can be enhanced by FKBP51 overexpression in mammalian cells, whereas FKBP12 is dispensable