Hartman et al., Oncogene 2009
(Carcinoma...) :
To determine whether folliculin , the product of the BHD gene, regulates mammalian target of rapamycin activity in vivo, we generated a mouse with targeted inactivation of the Bhd gene
Piao et al., Biochem Biophys Res Commun 2009
:
The function of FLCN has recently been implicated in the regulation of rapamycin-sensitive mTOR complex ( mTORC1 ) ... Reciprocally, the mTORC1 dependent phosphorylation of FLCN was reported