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IL3 — LEO1
Text-mined interactions from Literome
Kushikata et al., Neurosci Lett 2006
(Fever) :
PAF and its receptor are found in brain and PAF affects or is
affected by the production of sleep promoting cytokines such as
interleukin-1
Warringa et al., Blood 1991
:
We have investigated the modulatory
role of GM-CSF and
IL-3 on the
platelet activating factor (PAF)- , neutrophil activating factor ( NAF/IL-8 ) -, leukotriene B4 (LTB4)-, N-formyl-methionyl-leucyl-phenylalanine ( FMLP ) -, and human complement factor C5a induced chemotaxis of eosinophils from normal individuals
Wang et al., Mediators Inflamm 1996
:
Our previous studies have shown that EsA could reduce the release of
platelet activating factor (PAF) from rat macrophages, and
inhibit interleukin-1 and interleukin-6 production from routine macrophages
Bussolino et al., Biochim Biophys Acta 1987
:
These findings indicate that
interleukin 1
induces the
PAF synthesis by a deacylation/reacetylation mechanism into human endothelial cells
Saito et al., Int Arch Allergy Immunol 1993
:
These results suggest that
PAF induces the augmentation of
IL-3 production in CBMCs which in turn enhances differentiation into eosinophil-lineage cells
Dupuis et al., Res Immunol 1997
:
By contrast, M-CSF ( 1000 U/ml ), GM-CSF ( 100 ng/ml ), IL1,
IL3 , IL6 and stem cell factor ( 10 ng/ml ) did not
stimulate PAF production