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CCR6 — CD4
Text-mined interactions from Literome
Ravindran et al., Proc Natl Acad Sci U S A 2007
(Inflammation...) :
Furthermore, lymph node pathogen-specific
CD4 T cell activation
required CCR6 and cell migration from the site of infection
Rivino et al., J Exp Med 2010
:
Human
CD4 ( + ) CCR6 ( + ) memory T cells contained comparable numbers of IL-17- and IL-10 producing cells, and
CCR6 was
induced under both Th17 promoting conditions and upon tolerogenic T cell priming with transforming growth factor ( TGF ) -beta
Nakamoto et al., Gastroenterology 2012
(Disease Models, Animal...) :
Under inflammatory conditions,
CCR9 ( + ) macrophages
induced naive
CD4 ( + ) T cells to become interferon gamma producing Th1 cells in vivo and in vitro
Kim et al., PloS one 2013
:
Curcumin not merely blocks, but
regulates CD2/CD3/CD28 initiated
CD4 ( + ) T cell activation by augmenting CD69,
CCR7 , L-selectin and TGF-ß1 expression followed by regulatory T cell generation