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MAPK15 — TCF4

Text-mined interactions from Literome

Boyer et al., Nature 1999 : Interaction with human Sur-2 is also required for transcription to be activated by the activation domain of a transcription factor of the ETS-family in response to activated mitogen activated protein ( MAP ) kinase
Kawase et al., J Periodontal Res 1999 : In addition, CGRP 's activation of MAPK stimulated its ability to phosphorylate the Elk-1 transcription factor
Medvedev et al., J Immunol 2000 (MAP Kinase Signaling System) : In this study, the effect of in vitro endotoxin tolerance on LPS induced mitogen activated protein kinase activation, transcription factor induction , and cytokine, chemokine, and Toll-like receptor (TLR) 2 and 4 gene expression, as well as the involvement of TNF and IL-1 signaling pathways in tolerance, were examined
Ostrowski et al., J Hepatol 2000 : EGF, but not orthovanadate, activated nuclear AP-1 DNA binding activity in intact liver, indicating that activation of MAPK , p70S6k, and p90rsk by orthovanadate is not sufficient to activate this transcription factor
Thompson et al., Biochem Biophys Res Commun 2003 : Together, these results show that nuclear Ca ( 2+ ), MAPK , and cAMP each negatively regulate the activity of the TEAD transcription factor
Zhou et al., Toxicological sciences : an official journal of the Society of Toxicology 2003 : This study provides a novel model for studying the interrelationship of MAPK phosphorylation, transcription factor activation , and cytokine gene expression in an intact animal exposed to a toxic compound
Zeitlinger et al., Cell 2003 (MAP Kinase Signaling System) : Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling
Man et al., Mol Cell Biol 2003 (Mammary Neoplasms, Experimental) : The Ets2 transcription factor is regulated by mitogen activated protein ( MAP ) kinase phosphorylation of a single threonine residue
Olson et al., J Clin Invest 2004 (Insulin Resistance...) : Numerous stimuli activate Big MAPK-1 (BMK1), an MAPK that activates the myocyte enhancer factor-2 (MEF2) transcription factor
Weldon et al., Int J Oncol 2004 (Breast Neoplasms) : The involvement of p38-MAPK in the activation of the transcription factor , NF-kappaB, suggests a potential role and mechanism for regulation of cell survival and drug resistance
Butler et al., J Biol Chem 2005 : Finally we confirm the functional consequences of the activation of p38 MAPK by Pellino3 by demonstrating that Pellino3 promotes translocation of the p38 substrate, MAPK activated protein kinase2, from the nucleus to the cytoplasm and activates the transcription factor CREB in a p38 MAPK dependent manner
Park et al., Neurosci Lett 2006 (Neuroblastoma) : The mitogen activated protein kinase/extracellular signal regulated kinase ( MAPK/ERK ) activates a transcription factor CREB
Gee et al., J Biol Chem 2006 (MAP Kinase Signaling System) : Overall, our results suggest that intracellular HIV-Tat induces IL-10 transcription by ERK MAPK dependent CREB-1 transcription factor activation through Ser ( 133 ) phosphorylation
Eddy et al., Cell Biochem Funct 2007 : p38 MAPK regulation of transcription factor targets in muscle and heart of the hibernating bat, Myotis lucifugus
Vikman et al., J Neurosurg 2007 (Subarachnoid Hemorrhage) : In the present study, the authors evaluated the time course and sequence of the transduction pathways, p38 mitogen activated protein kinase ( MAPK ) and extracellular signal regulated kinase-1 and 2 ( ERK1/2 ), and associated transcription factor activation as well as gene regulation and associated protein levels
Bikkavilli et al., J Cell Sci 2008 : Chemical inhibitors of p38 MAPK ( SB203580 or SB239063 ) and expression of a dominant negative-version of p38 MAPK attenuate Wnt3a induced accumulation of beta-catenin, Lef/Tcf-sensitive gene activation, and primitive endoderm formation
Banerjee et al., Endocrinology 2009 : Downstream of ERK1/2, CG activates the nuclear transcription factor , Elk1, also in a PI3K-MAPK dependent manner
Boucher et al., Viral Immunol 2010 (HIV Infections...) : The role of MAPK signaling in transcription factor binding to the IL-12p40 promoter was subsequently determined
Egan et al., J Physiol 2010 : p38 mitogen activated protein kinase ( MAPK ) phosphorylation increased after both trials ( 2.0-fold, P < 0.05 ), but phosphorylation of the downstream transcription factor , activating transcription factor-2 ( ATF-2 ), increased only after HI ( 2.4-fold, P < 0.05 )
Butoi et al., Biochim Biophys Acta 2011 : Monocyte-SMC interaction induced the phosphorylation of p38MAPK and activation of AP-1 transcription factor
Katsch et al., Cell communication and signaling : CCS 2012 : Binding of Rho- and actin regulated MRTF : SRF complexes to target gene promoters requires an SRF binding site only, whereas MAPK regulated TCF : SRF complexes in addition rely on flanking sequences present in the serum response element ( SRE )
Zhou et al., J Biol Chem 2012 : The Sty1 MAPK regulates Atf1 transcription factor to elicit stress responses in extreme conditions of osmolarity and reactive oxygen species generating agents such as hydrogen peroxide, heat, low glucose, and heavy metal
Hu et al., Science 1996 : Several growth factors that inhibit fat cell differentiation caused mitogen activated protein ( MAP ) kinase mediated phosphorylation of the dominant adipogenic transcription factor peroxisome proliferator activated receptor gamma ( PPARgamma ) and reduction of its transcriptional activity
Bardwell et al., Genes Dev 1998 : Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK