Chatterjee et al., J Biol Chem 2011
:
Thus, agonist induced MAPK activation leads to Prdx6 phosphorylation and translocation to the cell membrane, where its PLA(2) activity facilitates assembly of the NOX2 complex and activation of the oxidase
Sorokina et al., Am J Physiol Cell Physiol 2011
(MAP Kinase Signaling System) :
These findings suggest that ERK and p38 MAPK regulate subcellular localization of Prdx6 by activation of 14-3-3e as a chaperone protein, resulting in its translocation to acidic organelles