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GRK1 — MAPK15

Text-mined interactions from Literome

Elorza et al., J Biol Chem 2003 : Interestingly, MAPK mediated modulation of wild-type GRK2 stability requires beta-arrestin function and is facilitated by previous phosphorylation of GRK2 on tyrosine residues by c-Src
Gao et al., Acta Biochim Biophys Sin (Shanghai) 2005 (MAP Kinase Signaling System) : Western blotting assay shows that EGF induced ERK/MAPK phosphorylation increases 1.9-fold, 1.1-fold and 1.5-fold ( P < 0.05 ) at time point 30, 60 and 120 min, respectively when the cells were transfected with GRK2, suggesting the regulatory role of GRK2 on EGF induced ERK/MAPK activation
Liu et al., J Immunol 2013 (MAP Kinase Signaling System) : We also show that LPS, through p38 MAPK signaling, induces phosphorylation of GRK2 at serine 670, which, in turn, suppresses GRK2 translocation to the membrane, thereby preventing GRK2 initiated internalization and desensitization of CCR2 in response to MCP-1