Gene interactions and pathways from curated databases and text-mining

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LRP1 — MMP3

Text-mined interactions from Literome

Emonard et al., Biochimie 2005 : Regulation of matrix metalloproteinase ( MMP ) activity by the low-density lipoprotein receptor related protein ( LRP )
Desrosiers et al., Pediatr Blood Cancer 2006 (Kidney Neoplasms...) : The proteolytic processing of MT1-MMP , a functional regulator of LRP , also correlated with the WT invasive phenotype
Suzuki et al., Blood 2009 (Brain Ischemia...) : Furthermore, inhibition of LRP suppressed both MMP-3 induction in endothelial cells and the increase in ICB by t-PA treatment after stroke
Suzuki et al., J Pharmacol Sci 2010 (Brain Ischemia...) : MMP-3 was upregulated by t-PA in endothelial cells, but the upregulation was prevented by the inhibition of either low-density lipoprotein receptor related protein ( LRP ) or nuclear factor kappa-B (NF-kappaB) activation