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LRP3 — WNT3

Text-mined interactions from Literome

Tamai et al., Nature 2000 : In Xenopus embryos, LRP6 activated Wnt-Fz signalling, and induced Wnt responsive genes, dorsal axis duplication and neural crest formation
Bafico et al., Nat Cell Biol 2001 : Wnt signalling through beta-catenin is mediated by the Fz receptor and a recently identified low-density-lipoprotein-receptor related co-receptor, LRP6/Arrow
Schweizer et al., BMC cell biology 2003 : Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
Semënov et al., J Biol Chem 2005 (Bone Diseases, Developmental) : We show here that SOST antagonizes Wnt signaling in Xenopus embryos and mammalian cells by binding to the extracellular domain of the Wnt coreceptors LRP5 and LRP6 and disrupting Wnt induced Frizzled-LRP complex formation
Stemmer et al., Oncogene 2008 (Colorectal Neoplasms) : Here, we demonstrate that snail increases Wnt reporter gene activity induced by beta-catenin, LRP6 or dishevelled, and also promotes transcription activated by GAL4-beta-catenin fusion proteins
Korol et al., Dev Biol 2008 : N1 does not bind LRP or Kremen nor inhibit Wnt signaling and has had no known function
Bhat et al., J Cell Biochem 2010 : DKK-1 protein blocks upregulation of the TCF-luciferase reporter by the Wnt3-Fz1 chimera, suggesting involvement of LRP in Wnt3-Fz1 signaling