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JUN — TLR3

Text-mined interactions from Literome

Janssens et al., FEBS Lett 2003 : MyD88 is an adapter protein that is involved in Toll-like receptor ( TLR ) - and interleukin-1 receptor (IL-1R) induced activation of nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK)
Maloney et al., J Biol Chem 2005 (MAP Kinase Signaling System) : Here, we show that A52R does not inhibit TLR induced p38 or c-Jun amino N-terminal kinase (JNK) mitogen activating protein ( MAP ) kinase activation
Wang et al., Nat Immunol 2006 : Tumor necrosis factor receptor associated factor 6 ( TRAF6 ) is critical for mediating Toll-like receptor ( TLR ) -interleukin 1 receptor (IL-1R) signaling and subsequent activation of NF-kappaB and AP-1 , transcriptional activators of innate immunity
Hu et al., J Leukoc Biol 2007 : IFN-gamma suppression of TLR induced activation of AP-1 and downstream target genes challenges current concepts about the inflammatory role of AP-1 proteins in macrophage activation and is consistent with a role for AP-1 in the generation of noninflammatory osteoclasts
Zhu et al., Biochem J 2010 : The mechanism was related to apoE suppression of TLR-agonist induced phosphorylation of JNK ( c-Jun N-terminal kinase ) and c-Jun
Wen et al., J Exp Med 2010 (Peritonitis...) : Rac1 activation is accompanied by JNK ( c-Jun N-terminal kinase ) and NF-?B activation, culminating in TLR induced binding of NF-?B and AP-1 to the promoters of inflammatory cytokines
Wang et al., Cell Microbiol 2013 (Atherosclerosis...) : Additionally, knock-down of JUN and FOS showed significantly decreased expression of Toll-like receptor (TLR)3 during infection, implicating JUN and FOS in TLR3 regulation