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ARG1 — JUN
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Christiansen et al., J Immunol 2002
(Rhinitis, Allergic, Perennial...) :
We demonstrated that
Lys-des-Arg-BK activates the transcription factor
AP-1
Peng et al., Blood 2004
:
AP1 binding absolutely
required Arg218 , Asp222, and Glu225
Liscovsky et al., Immunology 2009
:
The use of pharmacological specific inhibitors revealed that
arginase activity was dependent on p38 mitogen activated protein kinase ( MAPK ) and extracellular signal regulated protein kinase ( ERK ), but
independent of
c-Jun N-terminal kinase (JNK) activation
Zhu et al., Am J Physiol Cell Physiol 2010
:
Thrombin
induces endothelial
arginase through
AP-1 activation
Yu et al., Clin Cancer Res 2011
(Neoplasm Invasiveness...) :
Expression of the FGFR-4
Arg388 protein
leads to increased activity of the extracellular signal related kinase ( ERK ) pathway, increased activity of serum response factor (SRF) and
AP1 , and transcription of multiple genes that are correlated with aggressive clinical behavior in PCa