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MTOR — PRKAR2A
Text-mined interactions from Literome
Kim et al., Mol Cell Biol 2008
:
The antiapoptotic effect of GIP in beta cells is therefore partially mediated through a novel mode of transcriptional regulation of Bcl-2 involving
cAMP/PKA/AMPK dependent regulation of
CREB/TORC2 activity
Spirli et al., Hepatology 2010
(Cysts...) :
CONCLUSION : These data demonstrate that
PKA dependent up-regulation of
mTOR has a central role in the proliferative, antiapoptotic, and pro-angiogenic effects of IGF1 and VEGF in polycystin-2-defective mice
Xie et al., Cell Signal 2011
:
In this study, we show that the pharmacological elevation of [ cAMP ] ( i ) in mouse embryonic fibroblasts ( MEFs ) and human embryonic kidney 293 (HEK293) cells inhibits
mTORC1 activation via a
PKA dependent mechanism