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HSPG2 — PTK7

Text-mined interactions from Literome

Ting et al., J Exp Med 1992 : We have recently reported that PLC activation after Fc gamma R stimulation can be inhibited by a protein tyrosine kinase ( PTK ) inhibitor
Ortega et al., Biol Res 2005 : Therefore, it appears that more than one signaling pathway may be activated for the development of HR in lemon seedlings : one involving a G-protein and the other involving a PTK dependent PLC
Weiss et al., Semin Immunol 1991 : Recent studies suggest that the TCR activated PTK regulates PLC activation by the phosphorylation of tyrosine residues of PLC gamma 1
Yamashita et al., FEBS Lett 1991 : The results indicate that the PTK activity plays an essential role in the PLC activation through the T cell receptor/CD3 complex and through membrane Ig
Goldman et al., Biochem Biophys Res Commun 1994 : PtdIns-PLC activation was suppressed by down regulation or inhibition of PKC, by inhibition of NADPH oxidase activity and scavenging of its product, and by inhibitors of protein tyrosine kinase activity
Zheng et al., Infect Immun 1994 : The aim of the present study was to investigate whether protein tyrosine kinase ( PTK ) activity plays a role in the Fc gamma R-mediated intracellular killing of bacteria and activation of PLC in these cells ... Cross linking Fc gamma RI or Fc gamma RII induced rapid tyrosine phosphorylation of several proteins in monocytes, one of which was identified as PLC-gamma 1, and the phosphorylation could be completely blocked by PTK inhibitors, leading to the conclusion that activation of PLC after cross linking Fc gamma R in monocytes is regulated by PTK activity ... Together, these results demonstrate that PTK activity is essential for the activation of PLC which is involved in the Fc gamma R-mediated intracellular killing of S. aureus by human monocytes
Whalen et al., Immunology 1993 : These data indicate that a PTK is involved in the activation of NK PLC by tumour target cells in the cytotoxic response
Lim et al., Ind Health 1997 : The inhibitors of PTK and PLC suppressed the action of silica on the PLC activity
Kato et al., Int Arch Allergy Immunol 1998 (Asthma) : These findings suggest that at least two different pathways, i.e. PTK mediated G protein dependent or -independent PLC activation, are involved in the activation of human eosinophils