We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining
SHH: top 25 interacting genes (chr7:155592673-155605157)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only SHH-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-SHH interactions     Show top Genes on graph    

Less-frequently mentioned interactions with SHH, not among the Top 25
Other genes interacting with SHH. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ADAM17 ADCYAP1 AKT1 AKT2 AKT3 ANGPT1 BDNF
BMP1 BMP10 BMP15 BMP3 BMP5 BMP6 CASP3
CCNA2 CCNB1 CCND1 CDC2 CDH1 CDH10 CDH11
CDH12 CDH13 CDH15 CDH16 CDH17 CDH18 CDH19
CDH2 CDH20 CDH22 CDH23 CDH24 CDH26 CDH3
CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CDKN2A
CDON CTNNB1 DERL1 DERL2 DISP1 DISP2 EGF
EPHB2 EPO ERLEC1 FGF23 FGF5 FGF6 FGF9
FOXA1 FOXA2 FOXC1 FOXF1 FOXF2 GAS1 GBX2
GLI2 GLIS1 GLIS2 GLIS3 GPC3 GPC5 HAND2
HHIP HOXD11 HOXD13 IFNG IGF1 ISL1 LRP2
LRPAP1 MAP2K1 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13
MAPK14 MAPK15 MAPK3 MAPK4 MAPK6 MAPK7 MAPK8
MAPK9 MBD2 MMP9 MSX1 MYCN MYF5 MYLIP
NCOA3 NEUROD1 NEUROD2 NEUROD4 NEUROD6 NFKB1 NKX2-1
NKX2-2 NOG NOTCH1 NOTCH2 NOTCH3 NOTCH4 NOTUM
OLIG2 OPN1MW OS9 P4HB PAX2 PAX6 PCNA
PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCD
PTCH PTCH2 RELA RHOA RPS27A SEL1L SFRP1
SLC22A3 SLPI SMAD2 SMO SOD1 SOD2 SOD3
SOX14 SOX2 SOX9 STIL SYVN1 TAS2R38 TBX1
TBX2 TBX3 TCF12 TCF15 TCF19 TCF20 TCF21
TCF23 TCF24 TCF25 TCF3 TCF4 TCF7 TGFB1
TP53 TWIST1 UBA52 UBB UBC VCP VEGFA
WNT1 WNT11 WNT16 WNT2 WNT3 WNT4 WNT5A
WNT6 WNT7A ZIC2

Data information
Please see the Gene Interactions Track Manual.