UCSC Genome Browser Gene Interaction Graph

We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

IGF1R: top 25 interacting genes (chr15:99191767-99507759)

Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IGF1R-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.

Less-frequently mentioned interactions with IGF1R, not among the Top 25

Other genes interacting with IGF1R. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AMY2A ▸ ANXA6 ▸ APOB ▸ APP ▸ AR ▸ ARHGEF12 ▸ ARRB1 ▸
ARRB2 ▸ BRCA1 ▸ CA2 ▸ CAMP ▸ CASP1 ▸ CASP10 ▸ CASP12 ▸
CASP14 ▸ CASP16 ▸ CASP2 ▸ CASP3 ▸ CASP4 ▸ CASP5 ▸ CASP6 ▸
CASP7 ▸ CASP8 ▸ CASP9 ▸ CAT ▸ CAV1 ▸ CBL ▸ CCND1 ▸
CDH3 ▸ CRKL ▸ CSK ▸ CTNNA1 ▸ CTNNB1 ▸ CTNND1 ▸ DOK4 ▸
DOK5 ▸ DST ▸ EEA1 ▸ EFNA1 ▸ EFNA2 ▸ EFNA3 ▸ EFNA4 ▸
EFNA5 ▸ EGF ▸ EHD1 ▸ EPN1 ▸ EPN2 ▸ EPN3 ▸ EPS15 ▸
FFAR2 ▸ FGF2 ▸ FGF3 ▸ FIGF ▸ FN1 ▸ FOXO1 ▸ GAB1 ▸
GABBR1 ▸ GATA2 ▸ GH1 ▸ GIGYF1 ▸ GIPC1 ▸ GLMN ▸ GNA12 ▸
GNA13 ▸ GNAI1 ▸ GNAI2 ▸ GNAI3 ▸ GNAO1 ▸ GNAS ▸ GNAZ ▸
GRB14 ▸ GRB2 ▸ HIF1A ▸ HRAS ▸ HSP90AA1 ▸ HSP90AB1 ▸ HSPD1 ▸
IGFBP1 ▸ IGFBP2 ▸ IGFBP3 ▸ IGFBP5 ▸ IL6 ▸ IL6R ▸ ILK ▸
IRS2 ▸ IRS4 ▸ ITCH ▸ ITGB1 ▸ JAK1 ▸ JAK2 ▸ KITLG ▸
KL ▸ KRT27 ▸ MAP3K5 ▸ MAPK1 ▸ MAPK10 ▸ MAPK11 ▸ MAPK12 ▸
MAPK13 ▸ MAPK14 ▸ MAPK15 ▸ MAPK3 ▸ MAPK4 ▸ MAPK6 ▸ MAPK7 ▸
MAPK8 ▸ MAPK9 ▸ MDM2 ▸ NCK2 ▸ NEDD4 ▸ NEDD4L ▸ NFATC1 ▸
NGF ▸ NOTCH1 ▸ NRAS ▸ PDGFA ▸ PDGFB ▸ PDGFC ▸ PDGFD ▸
PELP1 ▸ PGF ▸ PIK3C2A ▸ PIK3C2B ▸ PIK3C2G ▸ PIK3CB ▸ PIK3CD ▸
PIK3CG ▸ PIK3R2 ▸ PIK3R3 ▸ PIK3R5 ▸ PLCG1 ▸ PLCG2 ▸ PRKAA1 ▸
PRKAA2 ▸ PRKAB1 ▸ PRKAB2 ▸ PRKACA ▸ PRKACB ▸ PRKACG ▸ PRKAG1 ▸
PRKAG2 ▸ PRKCD ▸ PRKD1 ▸ PRKX ▸ PRL ▸ PTEN ▸ PTPN1 ▸
PTPN11 ▸ RAF1 ▸ RAPGEF1 ▸ RASA1 ▸ RHOQ ▸ RNF41 ▸ RPL11 ▸
RPS6KB1 ▸ RPTOR ▸ RUVBL1 ▸ SFN ▸ SH2B1 ▸ SH3GL1 ▸ SH3GL2 ▸
SH3GL3 ▸ SH3GLB1 ▸ SH3GLB2 ▸ SH3KBP1 ▸ SHC1 ▸ SHC2 ▸ SHC3 ▸
SHC4 ▸ SIRPA ▸ SLC23A3 ▸ SMURF1 ▸ SMURF2 ▸ SNAP29 ▸ SOCS1 ▸
SOCS2 ▸ SOCS3 ▸ SORBS1 ▸ SOS1 ▸ SST ▸ STAT5B ▸ SUMO1 ▸
TAGLN ▸ TGFA ▸ THRA ▸ TRAF6 ▸ UBC ▸ VAV3 ▸ VEGFB ▸
VEGFC ▸ VHL ▸ WT1 ▸ WWP1 ▸ YWHAB ▸ YWHAE ▸ YWHAG ▸
YWHAH ▸ YWHAZ ▸ ZGLP1 ▸

Data information

Please see the Gene Interactions Track Manual.

AMY2A ▸	ANXA6 ▸	APOB ▸	APP ▸	AR ▸	ARHGEF12 ▸	ARRB1 ▸
ARRB2 ▸	BRCA1 ▸	CA2 ▸	CAMP ▸	CASP1 ▸	CASP10 ▸	CASP12 ▸
CASP14 ▸	CASP16 ▸	CASP2 ▸	CASP3 ▸	CASP4 ▸	CASP5 ▸	CASP6 ▸
CASP7 ▸	CASP8 ▸	CASP9 ▸	CAT ▸	CAV1 ▸	CBL ▸	CCND1 ▸
CDH3 ▸	CRKL ▸	CSK ▸	CTNNA1 ▸	CTNNB1 ▸	CTNND1 ▸	DOK4 ▸
DOK5 ▸	DST ▸	EEA1 ▸	EFNA1 ▸	EFNA2 ▸	EFNA3 ▸	EFNA4 ▸
EFNA5 ▸	EGF ▸	EHD1 ▸	EPN1 ▸	EPN2 ▸	EPN3 ▸	EPS15 ▸
FFAR2 ▸	FGF2 ▸	FGF3 ▸	FIGF ▸	FN1 ▸	FOXO1 ▸	GAB1 ▸
GABBR1 ▸	GATA2 ▸	GH1 ▸	GIGYF1 ▸	GIPC1 ▸	GLMN ▸	GNA12 ▸
GNA13 ▸	GNAI1 ▸	GNAI2 ▸	GNAI3 ▸	GNAO1 ▸	GNAS ▸	GNAZ ▸
GRB14 ▸	GRB2 ▸	HIF1A ▸	HRAS ▸	HSP90AA1 ▸	HSP90AB1 ▸	HSPD1 ▸
IGFBP1 ▸	IGFBP2 ▸	IGFBP3 ▸	IGFBP5 ▸	IL6 ▸	IL6R ▸	ILK ▸
IRS2 ▸	IRS4 ▸	ITCH ▸	ITGB1 ▸	JAK1 ▸	JAK2 ▸	KITLG ▸
KL ▸	KRT27 ▸	MAP3K5 ▸	MAPK1 ▸	MAPK10 ▸	MAPK11 ▸	MAPK12 ▸
MAPK13 ▸	MAPK14 ▸	MAPK15 ▸	MAPK3 ▸	MAPK4 ▸	MAPK6 ▸	MAPK7 ▸
MAPK8 ▸	MAPK9 ▸	MDM2 ▸	NCK2 ▸	NEDD4 ▸	NEDD4L ▸	NFATC1 ▸
NGF ▸	NOTCH1 ▸	NRAS ▸	PDGFA ▸	PDGFB ▸	PDGFC ▸	PDGFD ▸
PELP1 ▸	PGF ▸	PIK3C2A ▸	PIK3C2B ▸	PIK3C2G ▸	PIK3CB ▸	PIK3CD ▸
PIK3CG ▸	PIK3R2 ▸	PIK3R3 ▸	PIK3R5 ▸	PLCG1 ▸	PLCG2 ▸	PRKAA1 ▸
PRKAA2 ▸	PRKAB1 ▸	PRKAB2 ▸	PRKACA ▸	PRKACB ▸	PRKACG ▸	PRKAG1 ▸
PRKAG2 ▸	PRKCD ▸	PRKD1 ▸	PRKX ▸	PRL ▸	PTEN ▸	PTPN1 ▸
PTPN11 ▸	RAF1 ▸	RAPGEF1 ▸	RASA1 ▸	RHOQ ▸	RNF41 ▸	RPL11 ▸
RPS6KB1 ▸	RPTOR ▸	RUVBL1 ▸	SFN ▸	SH2B1 ▸	SH3GL1 ▸	SH3GL2 ▸
SH3GL3 ▸	SH3GLB1 ▸	SH3GLB2 ▸	SH3KBP1 ▸	SHC1 ▸	SHC2 ▸	SHC3 ▸
SHC4 ▸	SIRPA ▸	SLC23A3 ▸	SMURF1 ▸	SMURF2 ▸	SNAP29 ▸	SOCS1 ▸
SOCS2 ▸	SOCS3 ▸	SORBS1 ▸	SOS1 ▸	SST ▸	STAT5B ▸	SUMO1 ▸
TAGLN ▸	TGFA ▸	THRA ▸	TRAF6 ▸	UBC ▸	VAV3 ▸	VEGFB ▸
VEGFC ▸	VHL ▸	WT1 ▸	WWP1 ▸	YWHAB ▸	YWHAE ▸	YWHAG ▸
YWHAH ▸	YWHAZ ▸	ZGLP1 ▸